PubMed (NIH/NLM) records related to this compound for laboratory literature review. Inclusion does not imply suitability for any use beyond controlled research. Each note below is a research-framed summary using compliance-safe wording.
Showing 150 PubMed records. Displaying 10 per page.
- Zheng Y et al. (2023). MOTS-c: A promising mitochondrial-derived peptide for investigational exploitation [PMID: 36761202]
Laboratory literature summary: MOTS-c: A promising mitochondrial-derived peptide for investigational exploitation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Lee C et al. (2015). The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces… [PMID: 25738459]
Laboratory literature summary: The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces metabolic research models and insulin resistance. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Yin Y et al. (2024). Mitochondrial-Derived Peptide MOTS-c Suppresses Ovarian oncology research models… [PMID: 39321430]
Laboratory literature summary: Mitochondrial-Derived Peptide MOTS-c Suppresses Ovarian oncology research models Progression by Attenuating USP7-Mediated LARS1…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Yin Y et al. (2022). Laboratory research record on MOTS-C [PMID: 34798268]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Kim KH et al. (2018). The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate… [PMID: 29983246]
Laboratory literature summary: The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Li X et al. (2025). MOTS-c attenuates lung ischemia-reperfusion injury via MYH9-Dependent nuclear… [PMID: 40403491]
Laboratory literature summary: MOTS-c attenuates lung ischemia-reperfusion injury via MYH9-Dependent nuclear translocation and transcriptional activation of…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Gao Y et al. (2023). MOTS-c Functionally Prevents Metabolic Disorders [PMID: 36677050]
Laboratory literature summary: MOTS-c Functionally Prevents Metabolic Disorders. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kong BS et al. (2023). Laboratory research record on MOTS-C [PMID: 36824008]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Benayoun BA et al. (2019). MOTS-c: A Mitochondrial-Encoded Regulator of the Nucleus [PMID: 31378979]
Laboratory literature summary: MOTS-c: A Mitochondrial-Encoded Regulator of the Nucleus. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Jia H et al. (2024). Mitochondria-encoded peptide MOTS-c participates in plasma membrane repair by… [PMID: 39267782]
Laboratory literature summary: Mitochondria-encoded peptide MOTS-c participates in plasma membrane repair by facilitating the translocation of TRIM72 to membrane. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kong BS et al. (2025). Laboratory research record on MOTS-C [PMID: 40855115]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Yi X et al. (2023). Role of MOTS-c in the regulation of bone metabolism [PMID: 37200834]
Laboratory literature summary: Role of MOTS-c in the regulation of bone metabolism. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Lu P et al. (2023). The mitochondrial-derived peptide MOTS-c suppresses ferroptosis and alleviates acute… [PMID: 37290680]
Laboratory literature summary: The mitochondrial-derived peptide MOTS-c suppresses ferroptosis and alleviates acute lung injury induced by myocardial ischemia…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- García-Benlloch S et al. (2022). MOTS-c promotes muscle differentiation in vitro [PMID: 35842023]
Laboratory literature summary: MOTS-c promotes muscle differentiation in vitro. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Lee C et al. (2016). MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism [PMID: 27216708]
Laboratory literature summary: MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Zhang Z et al. (2023). MOTS-c: A potential anti-pulmonary fibrosis factor derived by mitochondria [PMID: 37307934]
Laboratory literature summary: MOTS-c: A potential anti-pulmonary fibrosis factor derived by mitochondria. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Wan W et al. (2023). Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress,… [PMID: 36670507]
Laboratory literature summary: Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kumagai H et al. (2021). MOTS-c reduces myostatin and muscle atrophy signaling [PMID: 33554779]
Laboratory literature summary: MOTS-c reduces myostatin and muscle atrophy signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Li K et al. (2025). MOTS-c attenuates mitochondrial dysfunction induces pyroptosis and cartilage… [PMID: 41043625]
Laboratory literature summary: MOTS-c attenuates mitochondrial dysfunction induces pyroptosis and cartilage degradation in osteoarthritis via an Nrf2-Dependent Mechanism. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Pham T et al. (2025). Laboratory research record on MOTS-C [PMID: 40661667]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Lin C et al. (2024). Novel function of MOTS-c in mitochondrial remodelling contributes to its antiviral… [PMID: 37788894]
Laboratory literature summary: Novel function of MOTS-c in mitochondrial remodelling contributes to its antiviral role during HBV infection. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Yoon TK et al. (2022). Exercise, Mitohormesis, and Mitochondrial ORF of the 12S rRNA Type-C (MOTS-c) [PMID: 35656563]
Laboratory literature summary: Exercise, Mitohormesis, and Mitochondrial ORF of the 12S rRNA Type-C (MOTS-c). Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Mohtashami Z et al. (2022). MOTS-c, the Most Recent Mitochondrial Derived Peptide in research subjects Aging and… [PMID: 36233287]
Laboratory literature summary: MOTS-c, the Most Recent Mitochondrial Derived Peptide in research subjects Aging and Age-Related Diseases. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Gudiksen A et al. (2026). MOTS-c improves intrinsic muscle mitochondrial bioenergetic health and efficiency in a… [PMID: 41520850]
Laboratory literature summary: MOTS-c improves intrinsic muscle mitochondrial bioenergetic health and efficiency in a PGC-1α/AMPK-dependent manner. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Fang T et al. (2025). Laboratory research record on MOTS-C [PMID: 41083123]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Liu S et al. (2026). Mitochondrial-derived peptide MOTS-c targets SLC7A11 to preserve spermatogenesis by… [PMID: 41933740]
Laboratory literature summary: Mitochondrial-derived peptide MOTS-c targets SLC7A11 to preserve spermatogenesis by suppressing ferroptosis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Shi J et al. (2026). MOTS-c, a mitochondrial-derived peptide, ameliorates lysosomal membrane permeability… [PMID: 42153537]
Laboratory literature summary: MOTS-c, a mitochondrial-derived peptide, ameliorates lysosomal membrane permeability and improves survival of soft tissue transplantation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Shen Z et al. (2025). MOTS-c Promotes Glycolysis via AMPK-HIF-1α-PFKFB3 Pathway to Ameliorate… [PMID: 40035775]
Laboratory literature summary: MOTS-c Promotes Glycolysis via AMPK-HIF-1α-PFKFB3 Pathway to Ameliorate Cardiopulmonary Bypass-induced Lung Injury. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Zou R et al. (2024). The DNA-dependent protein kinase catalytic subunit exacerbates endotoxemia-induced… [PMID: 38389837]
Laboratory literature summary: The DNA-dependent protein kinase catalytic subunit exacerbates endotoxemia-induced myocardial microvascular injury by disrupting the…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Bień J et al. (2024). MOTS-c regulates pancreatic alpha and beta cell functions in vitro [PMID: 38430258]
Laboratory literature summary: MOTS-c regulates pancreatic alpha and beta cell functions in vitro. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Elhusseiny R et al. (2026). Mitochondrial-derived peptides MOTS-c and humanin attenuate dexamethasone-induced… [PMID: 41732124]
Laboratory literature summary: Mitochondrial-derived peptides MOTS-c and humanin attenuate dexamethasone-induced atrophy in research subjects skeletal muscle cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Lin Y et al. (2025). MOTS-c-modified functional self-assembly peptide hydrogels enhance the activity of… [PMID: 40510834]
Laboratory literature summary: MOTS-c-modified functional self-assembly peptide hydrogels enhance the activity of nucleus pulposus-derived mesenchymal stem cells of…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Luo Z et al. (2025). Reduced serum levels of mitochondria-derived peptide MOTS-c in research subjects with… [PMID: 40538389]
Laboratory literature summary: Reduced serum levels of mitochondria-derived peptide MOTS-c in research subjects with obstructive sleep apnea. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Chen D et al. (2026). Mitochondria-derived peptide MOTS-c alleviates hyperoxia-induced bronchopulmonary… [PMID: 41802484]
Laboratory literature summary: Mitochondria-derived peptide MOTS-c alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice by activating Nrf2 pathway. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Ozkaya DY et al. (2025). MOTS-C levels ın ındividuals with and without metabolic research models and ıts… [PMID: 41004666]
Laboratory literature summary: MOTS-C levels ın ındividuals with and without metabolic research models and ıts association with ınflammation, insulin resistance and…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Zhang Y et al. (2024). The Mitochondrial-Derived Peptide MOTS-c Alleviates Radiation Pneumonitis via an… [PMID: 38790718]
Laboratory literature summary: The Mitochondrial-Derived Peptide MOTS-c Alleviates Radiation Pneumonitis via an Nrf2-Dependent Mechanism. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Ozturk Öztürk DA et al. (2024). Laboratory research record on MOTS-C [PMID: 38462167]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Chen F et al. (2025). Laboratory research record on MOTS-C [PMID: 40425777]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Edwards BA et al. (2025). Mitochondria-derived peptide MOTS-c and its role in OSA pathogenesis: a potential… [PMID: 40538382]
Laboratory literature summary: Mitochondria-derived peptide MOTS-c and its role in OSA pathogenesis: a potential investigational target?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Li Z et al. (2026). Laboratory research record on MOTS-C [PMID: 41710402]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Zhang YL et al. (2026). LAT1-mediated delivery of engineered R13A-MOTS-c attenuates radiation-induced lung… [PMID: 42142418]
Laboratory literature summary: LAT1-mediated delivery of engineered R13A-MOTS-c attenuates radiation-induced lung injury via Nrf2 activation and mitochondrial protection. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Bai Y et al. (2026). A mitochondrial-derived peptide MOTS-c contributes to the protective effect against… [PMID: 40753494]
Laboratory literature summary: A mitochondrial-derived peptide MOTS-c contributes to the protective effect against brain injury associated with LPS-induced sepsis by…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Lu H et al. (2019). MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic… [PMID: 30725119]
Laboratory literature summary: MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Yuan J et al. (2023). MOTS-c and aerobic exercise induce cardiac physiological adaptation via… [PMID: 36584915]
Laboratory literature summary: MOTS-c and aerobic exercise induce cardiac physiological adaptation via NRG1/ErbB4/CEBPβ modification in rats. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Fu Y et al. (2024). Laboratory research record on MOTS-C [PMID: 39616938]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Feng Y et al. (2025). Endurance training enhances skeletal muscle mitochondrial respiration by promoting… [PMID: 39706498]
Laboratory literature summary: Endurance training enhances skeletal muscle mitochondrial respiration by promoting MOTS-c secretion. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Li S et al. (2022). Laboratory research record on MOTS-C [PMID: 35370955]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Lu H et al. (2024). The mitochondrial genome-encoded peptide MOTS-c interacts with Bcl-2 to alleviate… [PMID: 38206815]
Laboratory literature summary: The mitochondrial genome-encoded peptide MOTS-c interacts with Bcl-2 to alleviate nonalcoholic steatohepatitis progression. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Luo YH et al. (2023). Laboratory research record on MOTS-C [PMID: 37077579]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Waldmann D et al. (2023). Exogenous humanin and MOTS-c function as protective agents against gentamicin-induced… [PMID: 37633181]
Laboratory literature summary: Exogenous humanin and MOTS-c function as protective agents against gentamicin-induced hair cell damage. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Lee C (2019). Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c [PMID: 31131297]
Laboratory literature summary: Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Chen D et al. (2026). MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced… [PMID: 41268602]
Laboratory literature summary: MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Saçmacı H et al. (2023). Laboratory research record on MOTS-C [PMID: 36303331]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Ran N et al. (2021). MOTS-c promotes phosphorodiamidate morpholino oligomer uptake and observed endpoints… [PMID: 33337582]
Laboratory literature summary: MOTS-c promotes phosphorodiamidate morpholino oligomer uptake and observed endpoints in dystrophic mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Wu J et al. (2023). The protective effect of the mitochondrial-derived peptide MOTS-c on LPS-induced… [PMID: 36786072]
Laboratory literature summary: The protective effect of the mitochondrial-derived peptide MOTS-c on LPS-induced septic cardiomyopathy. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Bhullar KS et al. (2021). Mitofusion is required for MOTS-c induced GLUT4 translocation [PMID: 34253808]
Laboratory literature summary: Mitofusion is required for MOTS-c induced GLUT4 translocation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Tok A et al. (2023). Serum MOTS-c levels remain unchanged in research subjects with preeclampsia [PMID: 39469962]
Laboratory literature summary: Serum MOTS-c levels remain unchanged in research subjects with preeclampsia. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Rodríguez-Esparragón F et al. (2025). Insights into the Biomarker Potential of Humanin and Mots-c Expression and Telomere… [PMID: 41303353]
Laboratory literature summary: Insights into the Biomarker Potential of Humanin and Mots-c Expression and Telomere Length in neurodegeneration research models's Disease. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Jiang J et al. (2023). Orally administered MOTS-c analogue ameliorates dextran sulfate sodium-induced colitis… [PMID: 36528071]
Laboratory literature summary: Orally administered MOTS-c analogue ameliorates dextran sulfate sodium-induced colitis by inhibiting inflammation and apoptosis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Feng Z et al. (2026). MOTS-c attenuates cardiac dysfunction following high altitude exposure by promoting… [PMID: 41654147]
Laboratory literature summary: MOTS-c attenuates cardiac dysfunction following high altitude exposure by promoting mitophagy. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Zempo H et al. (2021). A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c [PMID: 33468709]
Laboratory literature summary: A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Lu H et al. (2019). Mitochondrial-Derived Peptide MOTS-c Increases Adipose Thermogenic Activation to… [PMID: 31109005]
Laboratory literature summary: Mitochondrial-Derived Peptide MOTS-c Increases Adipose Thermogenic Activation to Promote Cold Adaptation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kutuk IS et al. (2026). Reduced serum and skeletal muscle MOTS c levels in research subjects with polycystic… [PMID: 41680431]
Laboratory literature summary: Reduced serum and skeletal muscle MOTS c levels in research subjects with polycystic ovary syndrome are associated with mitochondrial…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Wang M et al. (2022). Laboratory research record on MOTS-C [PMID: 36687680]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Li F et al. (2024). Neuroprotective Mechanism of MOTS-c in TBI Mice: Insights from Integrated… [PMID: 39050800]
Laboratory literature summary: Neuroprotective Mechanism of MOTS-c in TBI Mice: Insights from Integrated Transcriptomic and Metabolomic Analyses. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Saracaloglu A et al. (2023). Evaluation of Serum Humanin and MOTS-c Peptide Levels in research subjects with… [PMID: 36799414]
Laboratory literature summary: Evaluation of Serum Humanin and MOTS-c Peptide Levels in research subjects with COVID-19 and Healthy Subjects. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Zhong P et al. (2022). Mitochondrial derived peptide MOTS-c prevents the development of heart failure under… [PMID: 36156853]
Laboratory literature summary: Mitochondrial derived peptide MOTS-c prevents the development of heart failure under pressure overload conditions in mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Yoon SH et al. (2026). Systemic MOTS-c levels are increased in adults with metabolic research models in… [PMID: 41551324]
Laboratory literature summary: Systemic MOTS-c levels are increased in adults with metabolic research models in association with metabolic dysregulation and remain…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kong BS et al. (2021). Laboratory research record on MOTS-C [PMID: 34320351]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Ramanjaneya M et al. (2019). Lipids and insulin regulate mitochondrial-derived peptide (MOTS-c) in PCOS and healthy… [PMID: 31066084]
Laboratory literature summary: Lipids and insulin regulate mitochondrial-derived peptide (MOTS-c) in PCOS and healthy subjects. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Wu N et al. (2025). Laboratory research record on MOTS-C [PMID: 38141139]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Filibeli BE et al. (2026). Are serum MOTS-c levels and MOTS-c m.1382A>C polymorphism related to polycystic ovary… [PMID: 41945630]
Laboratory literature summary: Are serum MOTS-c levels and MOTS-c m.1382A>C polymorphism related to polycystic ovary syndrome?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Fuku N et al. (2015). The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity? [PMID: 26289118]
Laboratory literature summary: The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Ming W et al. (2016). Mitochondria related peptide MOTS-c suppresses ovariectomy-induced bone loss via AMPK… [PMID: 27237975]
Laboratory literature summary: Mitochondria related peptide MOTS-c suppresses ovariectomy-induced bone loss via AMPK activation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Li SH et al. (2026). MOTS-c attenuates hyperoxia-induced neonatal cardiac injury by inhibiting oxeiptosis… [PMID: 42128272]
Laboratory literature summary: MOTS-c attenuates hyperoxia-induced neonatal cardiac injury by inhibiting oxeiptosis via maintaining the KEAP1-PGAM5 interaction. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Leciejewska N et al. (2025). MOTS-c Impact on Muscle Cell Differentiation and Metabolism Across Fiber Types [PMID: 39876762]
Laboratory literature summary: MOTS-c Impact on Muscle Cell Differentiation and Metabolism Across Fiber Types. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Cuyàs E et al. (2022). Circulating levels of MOTS-c in research subjects with breast oncology research models… [PMID: 36490309]
Laboratory literature summary: Circulating levels of MOTS-c in research subjects with breast oncology research models studied with metformin. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Bień J et al. (2025). MOTS-c modulates pancreatic islet function in rats and pigs in vitro [PMID: 40478460]
Laboratory literature summary: MOTS-c modulates pancreatic islet function in rats and pigs in vitro. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kumagai H et al. (2022). The MOTS-c K14Q polymorphism in the mtDNA is associated with muscle fiber composition… [PMID: 34728329]
Laboratory literature summary: The MOTS-c K14Q polymorphism in the mtDNA is associated with muscle fiber composition and muscular performance. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Sidorenko DA et al. (2025). The impact of mitokine MOTS-c administration on the soleus muscle of rats subjected to… [PMID: 40608240]
Laboratory literature summary: The impact of mitokine MOTS-c administration on the soleus muscle of rats subjected to a 7-day hindlimb suspension. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Wang Z et al. (2024). Central and peripheral mechanism of MOTS-c attenuates pain hypersensitivity in a mice… [PMID: 37899006]
Laboratory literature summary: Central and peripheral mechanism of MOTS-c attenuates pain hypersensitivity in a mice model of inflammatory pain. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Yuan J et al. (2021). The mitochondrial signaling peptide MOTS-c improves myocardial performance during… [PMID: 34635713]
Laboratory literature summary: The mitochondrial signaling peptide MOTS-c improves myocardial performance during exercise training in rats. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Yu WD et al. (2021). The mitochondrial-derived peptide MOTS-c promotes homeostasis in aged research… [PMID: 33639272]
Laboratory literature summary: The mitochondrial-derived peptide MOTS-c promotes homeostasis in aged research subjects placenta-derived mesenchymal stem cells in vitro. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Reynolds JC et al. (2021). MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent… [PMID: 33473109]
Laboratory literature summary: MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Yaşar E et al. (2022). MOTS-c as a predictor of coronary lesions and complexity in research subjects with… [PMID: 36066139]
Laboratory literature summary: MOTS-c as a predictor of coronary lesions and complexity in research subjects with stable coronary artery disease. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Xiao J et al. (2023). The Mitochondrial-Derived Peptide (MOTS-c) Interacted with Nrf2 to Defend the… [PMID: 37380822]
Laboratory literature summary: The Mitochondrial-Derived Peptide (MOTS-c) Interacted with Nrf2 to Defend the Antioxidant System to Protect Dopaminergic Neurons Against…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Yan Z et al. (2019). MOTS-c inhibits Osteolysis in the Mouse Calvaria by affecting osteocyte-osteoclast… [PMID: 31369811]
Laboratory literature summary: MOTS-c inhibits Osteolysis in the Mouse Calvaria by affecting osteocyte-osteoclast crosstalk and inhibiting inflammation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Tang M et al. (2023). Laboratory research record on MOTS-C [PMID: 37957221]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Elhusseiny R et al. (2025). Repeated Heat Stress Modulates the Levels of the Mitokines MOTS-C and FGF21 in Active… [PMID: 40674654]
Laboratory literature summary: Repeated Heat Stress Modulates the Levels of the Mitokines MOTS-C and FGF21 in Active research subjects during Calf Muscle Immobilization. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Hyatt JK (2022). MOTS-c increases in skeletal muscle following long-term physical activity and improves… [PMID: 35808870]
Laboratory literature summary: MOTS-c increases in skeletal muscle following long-term physical activity and improves acute exercise performance after a single…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Wang J et al. (2024). Effect of Humanin and MOTS-c on ameliorating reproductive damage induced by… [PMID: 39079574]
Laboratory literature summary: Effect of Humanin and MOTS-c on ameliorating reproductive damage induced by prepubertal cyclophosphamide chemotherapy in research models…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kim SJ et al. (2019). MOTS-c: an equal opportunity insulin sensitizer [PMID: 30788534]
Laboratory literature summary: MOTS-c: an equal opportunity insulin sensitizer. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kim SJ et al. (2019). The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and… [PMID: 31293078]
Laboratory literature summary: The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin sensitivity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kim S (2024). The Relationship Between MOTS-c K14Q Polymorphism and Sarcopenia, Blood Lipids, and… [PMID: 39457696]
Laboratory literature summary: The Relationship Between MOTS-c K14Q Polymorphism and Sarcopenia, Blood Lipids, and Mental Health in Older Korean Adults. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kamiński K et al. (2024). Expression Patterns of MOTS-c in Adrenal Tumors: Results from a Preliminary Study [PMID: 39201408]
Laboratory literature summary: Expression Patterns of MOTS-c in Adrenal Tumors: Results from a Preliminary Study. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Baylan FA et al. (2021). Relationship between the mitochondria-derived peptide MOTS-c and insulin resistance in… [PMID: 33394327]
Laboratory literature summary: Relationship between the mitochondria-derived peptide MOTS-c and insulin resistance in obstructive sleep apnea. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Domin R et al. (2023). MOTS-c Serum Concentration Positively Correlates with Lower-Body Muscle Strength and… [PMID: 37834399]
Laboratory literature summary: MOTS-c Serum Concentration Positively Correlates with Lower-Body Muscle Strength and Is Not Related to Maximal Oxygen Uptake-A…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Zhai D et al. (2017). MOTS-c peptide increases survival and decreases bacterial load in mice infected with MRSA [PMID: 29096170]
Laboratory literature summary: MOTS-c peptide increases survival and decreases bacterial load in mice infected with MRSA. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Zicarelli M et al. (2025). MOTS-c Levels and Sarcopenia Risk in Chronic Peritoneal Dialysis research subjects: A… [PMID: 40005438]
Laboratory literature summary: MOTS-c Levels and Sarcopenia Risk in Chronic Peritoneal Dialysis research subjects: A Pilot Study. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kumagai H et al. (2024). Mitochondrial-derived microprotein MOTS-c attenuates immobilization-induced skeletal… [PMID: 38170165]
Laboratory literature summary: Mitochondrial-derived microprotein MOTS-c attenuates immobilization-induced skeletal muscle atrophy by suppressing lipid infiltration. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Jiang J et al. (2023). Mitochondrial-Derived Peptide MOTS-c Ameliorates Spared Nerve Injury-Induced… [PMID: 37285113]
Laboratory literature summary: Mitochondrial-Derived Peptide MOTS-c Ameliorates Spared Nerve Injury-Induced Neuropathic Pain in Mice by Inhibiting Microglia Activation…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Wei M et al. (2020). Mitochondrial-Derived Peptide MOTS-c Attenuates Vascular Calcification and Secondary… [PMID: 31694019]
Laboratory literature summary: Mitochondrial-Derived Peptide MOTS-c Attenuates Vascular Calcification and Secondary Myocardial Remodeling via Adenosine…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Liao Y et al. (2026). Humanin and MOTS-c Attenuate Atrial Fibrillation by Suppressing Fibrosis and… [PMID: 42193373]
Laboratory literature summary: Humanin and MOTS-c Attenuate Atrial Fibrillation by Suppressing Fibrosis and Mitochondrial Dysfunction. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Bolignano D et al. (2024). The Mitochondrial-Derived Peptide MOTS-c May Refine Mortality and Cardiovascular Risk… [PMID: 39111290]
Laboratory literature summary: The Mitochondrial-Derived Peptide MOTS-c May Refine Mortality and Cardiovascular Risk Prediction in Chronic Hemodialysis research…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Amado CA et al. (2023). Circulating levels of mitochondrial oxidative stress-related peptides MOTS-c and Romo1… [PMID: 36844198]
Laboratory literature summary: Circulating levels of mitochondrial oxidative stress-related peptides MOTS-c and Romo1 in stable COPD: A cross-sectional study. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kirik A et al. (2023). The relationship of circulating MOTS-c level with liver fibrosis and metabolic… [PMID: 37750635]
Laboratory literature summary: The relationship of circulating MOTS-c level with liver fibrosis and metabolic components in research subjects with metabolic…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Li YR et al. (2021). Laboratory research record on MOTS-C [PMID: 34914298]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Sánchez-Quintero MJ et al. (2025). Circulating PGC-1α and MOTS-c Peptide as Potential Mitochondrial Biomarkers in… [PMID: 40104672]
Laboratory literature summary: Circulating PGC-1α and MOTS-c Peptide as Potential Mitochondrial Biomarkers in research subjects Undergoing Aortic Valve Replacement. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Mills AR et al. (2026). Laboratory research record on MOTS-C [PMID: 42321010]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Cakmak A et al. (2025). MOTS-c as a Potential analytical assessment-prognostic Biomarker for Myocardial Infarction [PMID: 40353474]
Laboratory literature summary: MOTS-c as a Potential analytical assessment-prognostic Biomarker for Myocardial Infarction. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Shu X et al. (2025). Characterization of the Avian Mitochondrial-Derived Peptide MOTS-c and Its Potential… [PMID: 40805020]
Laboratory literature summary: Characterization of the Avian Mitochondrial-Derived Peptide MOTS-c and Its Potential Role as a Metabolic Regulator. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Kavak AG et al. (2024). Impact of Radiation research protocol on Serum Humanin and MOTS-c Levels in research… [PMID: 38314601]
Laboratory literature summary: Impact of Radiation research protocol on Serum Humanin and MOTS-c Levels in research subjects with Lung or Breast oncology research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Alser M et al. (2022). The Effect of Chronic Endurance Exercise on Serum Levels of MOTS-c and Humanin in… [PMID: 39077591]
Laboratory literature summary: The Effect of Chronic Endurance Exercise on Serum Levels of MOTS-c and Humanin in Professional Athletes. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Yang B et al. (2021). MOTS-c interacts synergistically with exercise intervention to regulate PGC-1α… [PMID: 33722744]
Laboratory literature summary: MOTS-c interacts synergistically with exercise intervention to regulate PGC-1α expression, attenuate insulin resistance and enhance…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Shen C et al. (2022). The Mitochondrial-Derived Peptide MOTS-c Attenuates Oxidative Stress Injury and the… [PMID: 34859377]
Laboratory literature summary: The Mitochondrial-Derived Peptide MOTS-c Attenuates Oxidative Stress Injury and the Inflammatory Response of H9c2 Cells Through the…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Santhanam SS et al. (2026). MOTS-c preserves mitochondrial subpopulation bioenergetics and genome integrity to… [PMID: 42228044]
Laboratory literature summary: MOTS-c preserves mitochondrial subpopulation bioenergetics and genome integrity to attenuate cardiac ischemia reperfusion injury. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Sequeira IR et al. (2021). Laboratory research record on MOTS-C [PMID: 34419510]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Cataldo LR et al. (2018). Laboratory research record on MOTS-C [PMID: 29593067]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Xing L et al. (2026). Mitochondrial-derived peptide MOTS-c activates metabolic signaling but blunts… [PMID: 42324588]
Laboratory literature summary: Mitochondrial-derived peptide MOTS-c activates metabolic signaling but blunts reparative function in research subjects mesenchymal…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Li Q et al. (2019). Earlier changes in mice after D-galactose investigation were improved by mitochondria… [PMID: 30967270]
Laboratory literature summary: Earlier changes in mice after D-galactose investigation were improved by mitochondria derived small peptide MOTS-c. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Santhanam SS et al. (2026). Exogenous MOTS-c mitigates myocardial ischemia-reperfusion injury: experimental and in… [PMID: 41593376]
Laboratory literature summary: Exogenous MOTS-c mitigates myocardial ischemia-reperfusion injury: experimental and in silico evidence from rat heart models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Qin Q et al. (2018). Downregulation of circulating MOTS-c levels in research subjects with coronary… [PMID: 29242099]
Laboratory literature summary: Downregulation of circulating MOTS-c levels in research subjects with coronary endothelial dysfunction. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Yang L et al. (2024). MOTS-c is an effective target for investigating oncology research models-induced bone… [PMID: 38716540]
Laboratory literature summary: MOTS-c is an effective target for investigating oncology research models-induced bone pain through the induction of AMPK-mediated…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- D'Souza RF et al. (2020). Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle… [PMID: 32182209]
Laboratory literature summary: Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging research subjects is associated…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Yin X et al. (2020). The intraperitoneal administration of MOTS-c produces antinociceptive and… [PMID: 31926126]
Laboratory literature summary: The intraperitoneal administration of MOTS-c produces antinociceptive and anti-inflammatory effects through the activation of AMPK…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Wojciechowska M et al. (2021). Changes in MOTS-c Level in the Blood of developmental research context research… [PMID: 34681131]
Laboratory literature summary: Changes in MOTS-c Level in the Blood of developmental research context research subjects with Metabolic Disorders. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Blatkiewicz M et al. (2026). MOTS-c primes adrenal cortex metabolism without directly driving steroidogenesis [PMID: 41811086]
Laboratory literature summary: MOTS-c primes adrenal cortex metabolism without directly driving steroidogenesis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Parseh S et al. (2024). Laboratory research record on MOTS-C [PMID: 38636847]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Xinqiang Y et al. (2020). Protective effect of MOTS-c on acute lung injury induced by lipopolysaccharide in mice [PMID: 31931370]
Laboratory literature summary: Protective effect of MOTS-c on acute lung injury induced by lipopolysaccharide in mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Asil H et al. (2024). Laboratory research record on MOTS-C [PMID: 39182552]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Du C et al. (2018). Laboratory research record on MOTS-C [PMID: 29691953]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Wen Z et al. (2024). The role of FPR2-mediated ferroptosis in formyl peptide-induced acute lung injury… [PMID: 38527401]
Laboratory literature summary: The role of FPR2-mediated ferroptosis in formyl peptide-induced acute lung injury against endothelial barrier damage and protective…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Jiang J et al. (2021). Peripheral Administration of a Cell-Penetrating MOTS-c Analogue Enhances Memory and… [PMID: 33861582]
Laboratory literature summary: Peripheral Administration of a Cell-Penetrating MOTS-c Analogue Enhances Memory and Attenuates Aβ(1-42)- or LPS-Induced Memory…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Jamnick NA et al. (2026). MOTS-c partially protects against skeletal muscle deterioration in C26 cachexia [PMID: 42266945]
Laboratory literature summary: MOTS-c partially protects against skeletal muscle deterioration in C26 cachexia. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Dieli-Conwright CM et al. (2021). Effect of aerobic and resistance exercise on the mitochondrial peptide MOTS-c in… [PMID: 34413391]
Laboratory literature summary: Effect of aerobic and resistance exercise on the mitochondrial peptide MOTS-c in Hispanic and Non-Hispanic White breast oncology…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Musolino M et al. (2026). MOTS-c is associated with oxidative stress and arterial stiffness in peritoneal… [PMID: 42126770]
Laboratory literature summary: MOTS-c is associated with oxidative stress and arterial stiffness in peritoneal dialysis research subjects: a pilot study. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Shen H et al. (2025). MOTS-c relieves hepatocellular carcinoma resistance to TRAIL-induced apoptosis under… [PMID: 39581216]
Laboratory literature summary: MOTS-c relieves hepatocellular carcinoma resistance to TRAIL-induced apoptosis under hypoxic conditions by activating MEF2A. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Liu C et al. (2019). Reduced skeletal muscle expression of mitochondrial-derived peptides humanin and… [PMID: 31432706]
Laboratory literature summary: Reduced skeletal muscle expression of mitochondrial-derived peptides humanin and MOTS-C and Nrf2 in chronic kidney disease. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Che N et al. (2019). MOTS-c improves osteoporosis by promoting the synthesis of type I collagen in… [PMID: 31081069]
Laboratory literature summary: MOTS-c improves osteoporosis by promoting the synthesis of type I collagen in osteoblasts via TGF-β/SMAD signaling pathway. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Guo Q et al. (2020). Adiponectin investigation improves insulin resistance in mice by regulating the… [PMID: 32880686]
Laboratory literature summary: Adiponectin investigation improves insulin resistance in mice by regulating the expression of the mitochondrial-derived peptide MOTS-c…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Raijmakers RPH et al. (2019). A possible role for mitochondrial-derived peptides humanin and MOTS-c in research… [PMID: 31088495]
Laboratory literature summary: A possible role for mitochondrial-derived peptides humanin and MOTS-c in research subjects with Q fever fatigue syndrome and chronic…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Ahn CH et al. (2020). Effects of MOTS-c on the mitochondrial function of cells harboring 3243 A to G mutant… [PMID: 32279209]
Laboratory literature summary: Effects of MOTS-c on the mitochondrial function of cells harboring 3243 A to G mutant mitochondrial DNA. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Li N et al. (2026). MOTS-c Protects Against Acetaminophen-induced Liver Injury through the MAPK Signaling… [PMID: 41764620]
Laboratory literature summary: MOTS-c Protects Against Acetaminophen-induced Liver Injury through the MAPK Signaling Pathway. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Sonay HO et al. (2026). Reduced Circulating MOTS-c Levels in Hashimoto's Thyroiditis Reflect Integrated… [PMID: 42278864]
Laboratory literature summary: Reduced Circulating MOTS-c Levels in Hashimoto's Thyroiditis Reflect Integrated Autoimmune and Metabolic Dysregulation: A…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Hu BT et al. (2018). MOTS-c improves osteoporosis by promoting osteogenic differentiation of bone marrow… [PMID: 30468456]
Laboratory literature summary: MOTS-c improves osteoporosis by promoting osteogenic differentiation of bone marrow mesenchymal stem cells via TGF-β/Smad pathway. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Weng FB et al. (2019). Laboratory research record on MOTS-C [PMID: 31858528]
PubMed laboratory record discussing MOTS-C in a research context. Review the full methods and limitations on PubMed; research use only.
- Knoop A et al. (2019). Development of a mass spectrometry based detection method for the… [PMID: 30394592]
Laboratory literature summary: Development of a mass spectrometry based detection method for the mitochondrion-derived peptide MOTS-c in plasma samples for doping…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Erol V et al. (2025). Serum Mitochondrial Open Reading Frame of the 12S rRNA-c (MOTS-c) Dynamics as a… [PMID: 41479490]
Laboratory literature summary: Serum Mitochondrial Open Reading Frame of the 12S rRNA-c (MOTS-c) Dynamics as a Complementary Marker of investigation Response in Newly…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Güvenir Seven S et al. (2026). Investigational Effects of MOTS-c in the Valproic Acid-Induced Autism Model in Rats:… [PMID: 41706383]
Laboratory literature summary: investigational Effects of MOTS-c in the Valproic Acid-Induced Autism Model in Rats: Role of Tetrahydrobiopterin and Brain-Derived…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
- Mohtashami Z et al. (2025). Exploring the investigational potential of MOTS-c in age-related macular degeneration:… [PMID: 39961901]
Laboratory literature summary: Exploring the investigational potential of MOTS-c in age-related macular degeneration: from cellular responses to research…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only
