IGF-1 LR3 Peptide research-grade
IGF-1 LR3 Peptide
$26.00 $90.00Price range: $26.00 through $90.00 Select options

IGF-1 LR3 Peptide

Price range: $26.00 through $90.00

Laboratory-grade IGF-1 LR3 Peptide is a long-arginine-3 analog of insulin-like growth factor-1 engineered for extended activity studies. Research buyers select this listing for pre-clinical work on IGF receptor signaling and cell-proliferation assay systems—not for clinical, veterinary, or consumer use.

For Research Use Only. Not for human use.

For Research Use Only — Not for Human Consumption
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For Research Use Only. Not for human use.

IGF-1 LR3 Peptide research-grade

Overview

Laboratory-grade IGF-1 LR3 Peptide presents as a long-arginine-3 analog of insulin-like growth factor-1 engineered for extended activity studies. Nationwide lists this SKU for controlled research programs focused on IGF receptor signaling and cell-proliferation assay systems—not for clinical, veterinary, or consumer use.

Research buyers specify IGF-1 LR3 Peptide when protocols require a characterized input for IGF receptor signaling and cell-proliferation assay systems. Typical deployments include cell-based or cell-free assays, method development plates, and pathway-mapping models executed under institutional laboratory SOPs.

Use this entry when laboratory purchasing needs a stable research SKU for assay construction and notebook traceability. All handling of IGF-1 LR3 Peptide must remain inside institutional research-use boundaries.

Research Context for IGF-1 LR3 Peptide

Work involving IGF-1 LR3 Peptide typically focuses on in vitro systems, assay development, and mechanistic model studies.

Teams confirm lot details before setup so conditions stay traceable across repeats and collaborative sites.

Published literature can inform starting ranges for related experimental designs. Each laboratory should still validate performance with its own instruments, plates, and detection chemistry.

Pilot runs are useful before committing larger plate sets, especially when detection chemistry or incubation windows are being optimized.

Documented Attributes

Key catalog attributes for this material include:

  • Research-grade material intended for laboratory investigation only
  • Catalog labeling aligned with research procurement channels
  • Suitable for method development and comparative assay workflows
  • Documentation packages available where provided for the listed lot

Laboratory Handling Notes

Receiving and Identity Checks

Before opening a vial of IGF-1 LR3 Peptide, confirm the physical label against the purchase order and packing list.

Retain outer packaging until identity checks are complete, and report damaged seals to purchasing before experimental work continues.

Reconstitution and Aliquoting

Handle this material according to institutional SOPs for weighing, reconstitution, aliquoting, and storage.

Record lot identifiers in laboratory notebooks before reconstitution. Verify solvent compatibility and storage temperature against your validated process.

Prepare assay buffers and consumables before opening the vial to reduce hold time. Keep unused aliquots labeled with date, solvent, and concentration for later repeats.

Chain of Custody

Keep chain-of-custody notes with inventory checks when material moves between freezers or benches.

Use dedicated spatulas and clean balances to avoid cross-contamination between catalog items. Schedule thaw cycles intentionally rather than repeated freeze-thaw of the same aliquot.

Secondary containment trays reduce spill risk during multi-step reconstitution. Cold-chain interruptions should be noted even when the vial remains sealed.

Why Laboratories Source IGF-1 LR3 Peptide

Procurement and research teams often select this catalog item because it supports:

  • Clear research-use labeling for compliance-aligned purchasing
  • Consistent product identification across multi-lot studies
  • Fit for reference, screening, and mechanistic laboratory models
  • Straightforward catalog support for planning and documentation

Study Planning and Quality Documentation

Before starting experimental work with IGF-1 LR3 Peptide, review any COA or quality files provided with the shipment.

Align your protocol with institutional research requirements and keep use within the labeled research context.

File catalog documentation with the study records at receipt. These steps help keep experiments comparable over time when using IGF-1 LR3 Peptide in sequential study phases.

Method Development Tips

Method development often begins with small pilot plates before larger screening panels.

Document buffer lots, incubation times, and detection settings alongside the material lot number.

If results diverge from historical baselines, re-check reconstitution volume and storage history first. Shared equipment logs help explain variance when multiple operators run the same protocol.

Inventory and Training

Update digital inventory immediately after opening a new lot of IGF-1 LR3 Peptide.

Training new staff on labeling conventions reduces mix-ups across similar catalog SKUs. When transferring methods between sites, share both the written SOP and the lot metadata package.

Dispose of residual solutions according to institutional chemical hygiene rules. Do not repurpose research materials for any non-laboratory application.

Periodic inventory reconciliation keeps expired or depleted lots from entering active workflows. For related catalog options, browse adjacent research categories on this site after confirming your assay needs.

For Research Use Only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease.

Peptide Research

For Research Use Only. Not for human use.

PubMed (NIH/NLM) records related to this compound for laboratory literature review. Inclusion does not imply suitability for any use beyond controlled research. Each note below is a research-framed summary using compliance-safe wording.

Showing 509 PubMed records. Displaying 10 per page.

  1. Fanti M et al. (2024). Nutrition, GH/IGF-1 signaling, and oncology research models [PMID: 39166749]

    Laboratory literature summary: Nutrition, GH/IGF-1 signaling, and oncology research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  2. García-Arnés JA et al. (2023). Doping and sports endocrinology: growth hormone, IGF-1, insulin, and erythropoietin [PMID: 36736729]

    Laboratory literature summary: Doping and sports endocrinology: growth hormone, IGF-1, insulin, and erythropoietin. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  3. Yan J et al. (2016). Gut microbiota induce IGF-1 and promote bone formation and growth [PMID: 27821775]

    Laboratory literature summary: Gut microbiota induce IGF-1 and promote bone formation and growth. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  4. Li K et al. (2023). The AR/miR-221/IGF-1 pathway mediates the pathogenesis of androgenetic alopecia [PMID: 37496996]

    Laboratory literature summary: The AR/miR-221/IGF-1 pathway mediates the pathogenesis of androgenetic alopecia. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  5. Higashi Y et al. (2019). IGF-1 and cardiovascular disease [PMID: 30735831]

    Laboratory literature summary: IGF-1 and cardiovascular disease. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  6. Yan J et al. (2018). Gut Microbiota and IGF-1 [PMID: 29362822]

    Laboratory literature summary: Gut Microbiota and IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  7. Zhang WB et al. (2022). Looking at IGF-1 through the hourglass [PMID: 36063137]

    Laboratory literature summary: Looking at IGF-1 through the hourglass. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  8. Higashi Y et al. (2012). Aging, atherosclerosis, and IGF-1 [PMID: 22491965]

    Laboratory literature summary: Aging, atherosclerosis, and IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  9. Lee WS et al. (2024). New Insights into IGF-1 Signaling in the Heart [PMID: 38713091]

    Laboratory literature summary: New Insights into IGF-1 Signaling in the Heart. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  10. Martín AI et al. (2021). IGF-1 and IGFBP-3 in Inflammatory Cachexia [PMID: 34502376]

    Laboratory literature summary: IGF-1 and IGFBP-3 in Inflammatory Cachexia. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  11. Higashi Y et al. (2010). IGF-1, oxidative stress and atheroprotection [PMID: 20071192]

    Laboratory literature summary: IGF-1, oxidative stress and atheroprotection. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  12. Ling SC (1996). Laboratory research record on IGF-1 LR3 [PMID: 8708895]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  13. Cirrik S et al. (2018). IGF-1 receptor cleavage in hypertension [PMID: 29556095]

    Laboratory literature summary: IGF-1 receptor cleavage in hypertension. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  14. Orrù S et al. (2017). A Functional Interplay between IGF-1 and Adiponectin [PMID: 29036907]

    Laboratory literature summary: A Functional Interplay between IGF-1 and Adiponectin. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  15. Baht GS et al. (2020). Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism [PMID: 32694780]

    Laboratory literature summary: Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  16. Pfäffle R et al. (2020). GH and IGF-1 Replacement in Children [PMID: 31932988]

    Laboratory literature summary: GH and IGF-1 Replacement in Children. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  17. Jia T et al. (2014). IGF-1 and survival in ESRD [PMID: 24178975]

    Laboratory literature summary: IGF-1 and survival in ESRD. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  18. Lv KJ et al. (2024). Oncology research models-associated fibroblasts promote the progression and… [PMID: 39241901]

    Laboratory literature summary: oncology research models-associated fibroblasts promote the progression and chemoresistance of HCC by inducing IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  19. Anversa P (2005). Aging and longevity: the IGF-1 enigma [PMID: 16141115]

    Laboratory literature summary: Aging and longevity: the IGF-1 enigma. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  20. Tian F et al. (2018). IGF-1 signaling mediated cell-specific skeletal mechano-transduction [PMID: 28980721]

    Laboratory literature summary: IGF-1 signaling mediated cell-specific skeletal mechano-transduction. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  21. Obradovic M et al. (2019). Effects of IGF-1 on the Cardiovascular System [PMID: 31692426]

    Laboratory literature summary: Effects of IGF-1 on the Cardiovascular System. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  22. van Heemst D (2010). Insulin, IGF-1 and longevity [PMID: 22396862]

    Laboratory literature summary: Insulin, IGF-1 and longevity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  23. Zhong W et al. (2023). Metabolic research models and endocrine-related oncology research models: The… [PMID: 36755926]

    Laboratory literature summary: metabolic research models and endocrine-related oncology research models: The important role of IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  24. Sarver DC et al. (2024). Tmem263 deletion disrupts the GH/IGF-1 axis and causes dwarfism and impairs skeletal… [PMID: 38241182]

    Laboratory literature summary: Tmem263 deletion disrupts the GH/IGF-1 axis and causes dwarfism and impairs skeletal acquisition. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  25. Józefiak A et al. (2021). The IGF-1 Signaling Pathway in Viral Infections [PMID: 34452353]

    Laboratory literature summary: The IGF-1 Signaling Pathway in Viral Infections. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  26. Kavran JM et al. (2014). How IGF-1 activates its receptor [PMID: 25255214]

    Laboratory literature summary: How IGF-1 activates its receptor. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  27. Li X et al. (2024). When IGF-1 Meets Metabolic Inflammation and Polycystic Ovary Syndrome [PMID: 38941670]

    Laboratory literature summary: When IGF-1 Meets Metabolic Inflammation and Polycystic Ovary Syndrome. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  28. Musarò A et al. (2019). Counteracting sarcopenia: the role of IGF-1 isoforms [PMID: 31195371]

    Laboratory literature summary: Counteracting sarcopenia: the role of IGF-1 isoforms. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  29. Junnila RK et al. (2013). The GH/IGF-1 axis in ageing and longevity [PMID: 23591370]

    Laboratory literature summary: The GH/IGF-1 axis in ageing and longevity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  30. Renna M et al. (2013). IGF-1 receptor antagonism inhibits autophagy [PMID: 23804751]

    Laboratory literature summary: IGF-1 receptor antagonism inhibits autophagy. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  31. Bhalla S et al. (2022). Protective role of IGF-1 and GLP-1 signaling activation in neurological dysfunctions [PMID: 36191807]

    Laboratory literature summary: Protective role of IGF-1 and GLP-1 signaling activation in neurological dysfunctions. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  32. Baserga R et al. (2003). The IGF-1 receptor in oncology research models biology [PMID: 14601044]

    Laboratory literature summary: The IGF-1 receptor in oncology research models biology. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  33. Mangiola A et al. (2015). Role and Importance of IGF-1 in Traumatic Brain Injuries [PMID: 26417600]

    Laboratory literature summary: Role and Importance of IGF-1 in Traumatic Brain Injuries. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  34. Smith LE (2005). IGF-1 and retinopathy of prematurity in the preterm infant [PMID: 16210846]

    Laboratory literature summary: IGF-1 and retinopathy of prematurity in the preterm infant. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  35. Jiang J et al. (2017). Sevoflurane downregulates IGF‑1 via microRNA‑98 [PMID: 28260068]

    Laboratory literature summary: Sevoflurane downregulates IGF‑1 via microRNA‑98. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  36. Dees WL et al. (2021). IGF-1 Influences Gonadotropin-Releasing Hormone Regulation of Puberty [PMID: 33406521]

    Laboratory literature summary: IGF-1 Influences Gonadotropin-Releasing Hormone Regulation of Puberty. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  37. Baxter RC (2015). How IGF-1 activates its receptor [PMID: 25711905]

    Laboratory literature summary: How IGF-1 activates its receptor. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  38. Conti E et al. (2011). IGF-1 and atherothrombosis: relevance to pathophysiology and research protocol [PMID: 21244364]

    Laboratory literature summary: IGF-1 and atherothrombosis: relevance to pathophysiology and research protocol. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  39. Holzenberger M et al. (2004). IGF-1 signaling and aging [PMID: 15582293]

    Laboratory literature summary: IGF-1 signaling and aging. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  40. Penn MS et al. (2010). IGF-1 and mechanisms of myocardial repair [PMID: 19535158]

    Laboratory literature summary: IGF-1 and mechanisms of myocardial repair. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  41. Hede MS et al. (2012). E-peptides control bioavailability of IGF-1 [PMID: 23251442]

    Laboratory literature summary: E-peptides control bioavailability of IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  42. Chuard A et al. (2025). Viral insulin/IGF-like peptides inhibit IGF-1 receptor signaling to enhance viral… [PMID: 40829596]

    Laboratory literature summary: Viral insulin/IGF-like peptides inhibit IGF-1 receptor signaling to enhance viral replication. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  43. Yakar S et al. (2010). IGF-1 and bone: New discoveries from mouse models [PMID: 20836088]

    Laboratory literature summary: IGF-1 and bone: New discoveries from mouse models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  44. Druckmann R et al. (2002). IGF-1 in gynaecology and obstetrics: update 2002 [PMID: 11955796]

    Laboratory literature summary: IGF-1 in gynaecology and obstetrics: update 2002. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  45. Arai Y et al. (2009). The metabolic syndrome, IGF-1, and insulin action [PMID: 18672019]

    Laboratory literature summary: The metabolic syndrome, IGF-1, and insulin action. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  46. Zhang H et al. (2025). Chrysophanol delays aging via insulin/IGF-1 signaling pathway [PMID: 40086491]

    Laboratory literature summary: Chrysophanol delays aging via insulin/IGF-1 signaling pathway. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  47. Armakolas N et al. (2016). The role of the IGF-1 Ec in myoskeletal system and oncology research models… [PMID: 27931832]

    Laboratory literature summary: The role of the IGF-1 Ec in myoskeletal system and oncology research models pathophysiology. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  48. Maglio LE et al. (2021). IGF-1 facilitates extinction of conditioned fear [PMID: 33792539]

    Laboratory literature summary: IGF-1 facilitates extinction of conditioned fear. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  49. Laron Z (2004). IGF-1 and insulin as growth hormones [PMID: 15562823]

    Laboratory literature summary: IGF-1 and insulin as growth hormones. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  50. Rincon M et al. (2005). The insulin/IGF-1 signaling in mammals and its relevance to research subjects longevity [PMID: 16168602]

    Laboratory literature summary: The insulin/IGF-1 signaling in mammals and its relevance to research subjects longevity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  51. Abbas A et al. (2008). Role of IGF-1 in glucose regulation and cardiovascular disease [PMID: 18793116]

    Laboratory literature summary: Role of IGF-1 in glucose regulation and cardiovascular disease. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  52. Gow DJ et al. (2010). CSF-1, IGF-1, and the control of postnatal growth and development [PMID: 20519640]

    Laboratory literature summary: CSF-1, IGF-1, and the control of postnatal growth and development. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  53. Roberts CT Jr (2004). IGF-1 and prostate oncology research models [PMID: 15562830]

    Laboratory literature summary: IGF-1 and prostate oncology research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  54. Werner H et al. (2012). IGF-1 and BRCA1 signalling pathways in familial oncology research models [PMID: 23182194]

    Laboratory literature summary: IGF-1 and BRCA1 signalling pathways in familial oncology research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  55. Bassil F et al. (2014). Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: targets for disease… [PMID: 24582776]

    Laboratory literature summary: Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: targets for disease modification?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  56. Selicharová I et al. (2026). An engineered insulin analog with dual insulin and IGF-1 receptor agonism and distinct… [PMID: 42139356]

    Laboratory literature summary: An engineered insulin analog with dual insulin and IGF-1 receptor agonism and distinct signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  57. Salvatori R (2004). Growth hormone and IGF-1 [PMID: 14966386]

    Laboratory literature summary: Growth hormone and IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  58. Larsson SC et al. (2020). IGF-1 and cardiometabolic diseases: a Mendelian randomisation study [PMID: 32548700]

    Laboratory literature summary: IGF-1 and cardiometabolic diseases: a Mendelian randomisation study. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  59. Yang P et al. (2025). HVT-delivered chicken IGF-1 improves growth performance in broilers [PMID: 40784053]

    Laboratory literature summary: HVT-delivered chicken IGF-1 improves growth performance in broilers. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  60. Macvanin M et al. (2023). New insights on the cardiovascular effects of IGF-1 [PMID: 36843588]

    Laboratory literature summary: New insights on the cardiovascular effects of IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  61. O'Neill C et al. (2012). Insulin and IGF-1 signalling: longevity, protein homoeostasis and neurodegeneration… [PMID: 22817723]

    Laboratory literature summary: Insulin and IGF-1 signalling: longevity, protein homoeostasis and neurodegeneration research models's disease. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  62. Xu X et al. (2025). IGF-1 Provides Protective Role in Arteriosclerotic Cerebral Small Vessel Disease [PMID: 40248881]

    Laboratory literature summary: IGF-1 Provides Protective Role in Arteriosclerotic Cerebral Small Vessel Disease. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  63. Walenkamp MJ et al. (2013). Molecular IGF-1 and IGF-1 receptor defects: from genetics to laboratory management [PMID: 23392101]

    Laboratory literature summary: Molecular IGF-1 and IGF-1 receptor defects: from genetics to laboratory management. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  64. Feng Z (2010). P53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment [PMID: 20182617]

    Laboratory literature summary: p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  65. Savage MO (2013). Phenotypes, investigation and investigation of primary IGF-1 deficiency [PMID: 23392102]

    Laboratory literature summary: Phenotypes, investigation and investigation of primary IGF-1 deficiency. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  66. Rajoria B et al. (2023). IGF-1 Stimulates Glycolytic ATP Production in MCF-7L Cells [PMID: 37373357]

    Laboratory literature summary: IGF-1 Stimulates Glycolytic ATP Production in MCF-7L Cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  67. Elijah IE et al. (2011). The GH/IGF-1 system in critical illness [PMID: 21925076]

    Laboratory literature summary: The GH/IGF-1 system in critical illness. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  68. Toodle V et al. (2022). Fluconazole Is Neuroprotective via Interactions with the IGF-1 Receptor [PMID: 35831747]

    Laboratory literature summary: Fluconazole Is Neuroprotective via Interactions with the IGF-1 Receptor. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  69. Papadimitriou A et al. (2022). Growth variations with opposite laboratory outcomes and the emerging role of IGF-1 [PMID: 35331614]

    Laboratory literature summary: Growth variations with opposite laboratory outcomes and the emerging role of IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  70. Majchrzak-Baczmańska D et al. (2016). Does IGF-1 play a role in the biology of endometrial oncology research models? [PMID: 27629137]

    Laboratory literature summary: Does IGF-1 play a role in the biology of endometrial oncology research models?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  71. Kraemer WJ et al. (2017). Recovery responses of androgen-pathway markers, growth hormone, and IGF-1 after… [PMID: 27856715]

    Laboratory literature summary: Recovery responses of androgen-pathway markers, growth hormone, and IGF-1 after resistance exercise. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  72. Shanmugalingam T et al. (2016). Is there a role for IGF-1 in the development of second primary cancers? [PMID: 27734632]

    Laboratory literature summary: Is there a role for IGF-1 in the development of second primary cancers?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  73. Loprinzi PD (2019). IGF-1 in exercise-induced enhancement of episodic memory [PMID: 29938915]

    Laboratory literature summary: IGF-1 in exercise-induced enhancement of episodic memory. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  74. Darlow BA et al. (2018). Oxygen, weight gain, IGF-1 and ROP: not a straight-forward equation [PMID: 29083092]

    Laboratory literature summary: Oxygen, weight gain, IGF-1 and ROP: not a straight-forward equation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  75. Nandakumar AM et al. (2025). IGF-1 regulates oncology research models cell immune evasion in prostate oncology… [PMID: 41184420]

    Laboratory literature summary: IGF-1 regulates oncology research models cell immune evasion in prostate oncology research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  76. Bhattacharjee A et al. (2026). Doxycycline and IGF-1 as a synergistic combination research protocol for OA disease… [PMID: 41401641]

    Laboratory literature summary: Doxycycline and IGF-1 as a synergistic combination research protocol for OA disease modification. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  77. Zeng L et al. (2024). IGF-1's protective effect on OSAS rats' learning and memory [PMID: 38858326]

    Laboratory literature summary: IGF-1's protective effect on OSAS rats' learning and memory. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  78. Lønning PE et al. (2004). IGF-1 and breast oncology research models [PMID: 15562831]

    Laboratory literature summary: IGF-1 and breast oncology research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  79. Gatenby VK et al. (2013). The IGF-1 receptor and regulation of nitric oxide bioavailability and insulin… [PMID: 23338941]

    Laboratory literature summary: The IGF-1 receptor and regulation of nitric oxide bioavailability and insulin signalling in the endothelium. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  80. Sohrabji F (2015). Laboratory research record on IGF-1 LR3 [PMID: 24882635]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  81. Ravi P et al. (2023). IGF-1 axis changes with ADT and docetaxel in metastatic prostate oncology research models [PMID: 37671811]

    Laboratory literature summary: IGF-1 axis changes with ADT and docetaxel in metastatic prostate oncology research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  82. Karino K et al. (2025). ADAM9 Promotes Glycolysis in Th17 Cells and Autoimmunity Through Activation of IGF-1… [PMID: 40915982]

    Laboratory literature summary: ADAM9 Promotes Glycolysis in Th17 Cells and Autoimmunity Through Activation of IGF-1 Signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  83. Wahyuni T et al. (2021). Maresin-1 induces cardiomyocyte hypertrophy through IGF-1 paracrine pathway [PMID: 34038245]

    Laboratory literature summary: Maresin-1 induces cardiomyocyte hypertrophy through IGF-1 paracrine pathway. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  84. Timmer LT et al. (2018). The Role of IGF-1 Signaling in Skeletal Muscle Atrophy [PMID: 30390250]

    Laboratory literature summary: The Role of IGF-1 Signaling in Skeletal Muscle Atrophy. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  85. Hou YL et al. (2022). IGF-1 Accelerates Cell Aging by Inhibiting POLD1 Expression [PMID: 36443251]

    Laboratory literature summary: IGF-1 Accelerates Cell Aging by Inhibiting POLD1 Expression. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  86. Sasako T et al. (2016). [Insulin/IGF-1 signaling and aging] [PMID: 30557473]

    Laboratory literature summary: [Insulin/IGF-1 signaling and aging]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  87. Park J et al. (2026). Celastrol and Cblin peptide activation of IGF-1 signaling prevents… [PMID: 41252406]

    Laboratory literature summary: Celastrol and Cblin peptide activation of IGF-1 signaling prevents microgravity-induced atrophy in rat L6 myotubes. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  88. Saneyasu T et al. (2022). IGF-1 knockdown inhibits phosphorylation of Akt and ERK in chicken embryonic myotubes [PMID: 35717687]

    Laboratory literature summary: IGF-1 knockdown inhibits phosphorylation of Akt and ERK in chicken embryonic myotubes. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  89. Irie HY et al. (2010). PTK6 regulates IGF-1-induced anchorage-independent survival [PMID: 20668531]

    Laboratory literature summary: PTK6 regulates IGF-1-induced anchorage-independent survival. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  90. Teng Chung T et al. (2006). Investigation with GH and IGF-1 in critical illness [PMID: 16399018]

    Laboratory literature summary: investigation with GH and IGF-1 in critical illness. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  91. Muhammad T et al. (2023). Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling [PMID: 36892215]

    Laboratory literature summary: Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  92. Bonjour JP et al. (1997). Protein intake, IGF-1 and osteoporosis [PMID: 9536300]

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  93. Pfäffle R et al. (2011). From GHRH to IGF-1 and downstream: laboratory phenotypes and biological mechanisms [PMID: 22423511]

    Laboratory literature summary: From GHRH to IGF-1 and downstream: laboratory phenotypes and biological mechanisms. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  94. Grigorescu F et al. (1994). Insulin and IGF-1 signaling in oocyte maturation [PMID: 7959635]

    Laboratory literature summary: Insulin and IGF-1 signaling in oocyte maturation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  95. Guan X et al. (2022). IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation [PMID: 35334906]

    Laboratory literature summary: IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  96. Caverzasio J et al. (1992). [IGF-1 and phosphate homeostasis during growth] [PMID: 1641052]

    Laboratory literature summary: [IGF-1 and phosphate homeostasis during growth]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  97. Chrudinová M et al. (2024). A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates… [PMID: 38182007]

    Laboratory literature summary: A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  98. Man AWC et al. (2025). L-Citrulline Improves IGF-1 Signaling Pathway in Preeclampsia via Polyamines [PMID: 40452593]

    Laboratory literature summary: L-Citrulline Improves IGF-1 Signaling Pathway in Preeclampsia via Polyamines. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  99. Bruchim I et al. (2013). Targeting IGF-1 signaling pathways in gynecologic malignancies [PMID: 23294364]

    Laboratory literature summary: Targeting IGF-1 signaling pathways in gynecologic malignancies. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  100. Geffken SJ et al. (2022). Insulin and IGF-1 elicit robust transcriptional regulation to modulate autophagy in… [PMID: 36503893]

    Laboratory literature summary: Insulin and IGF-1 elicit robust transcriptional regulation to modulate autophagy in astrocytes. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  101. Thevis M et al. (2010). Mass spectrometry-based analysis of IGF-1 and hGH [PMID: 20020366]

    Laboratory literature summary: Mass spectrometry-based analysis of IGF-1 and hGH. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  102. Sherlala RA et al. (2021). Laboratory research record on IGF-1 LR3 [PMID: 33180942]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  103. Giuffrida ML et al. (2012). Beta-amyloid monomer and insulin/IGF-1 signaling in neurodegeneration research… [PMID: 22886436]

    Laboratory literature summary: Beta-amyloid monomer and insulin/IGF-1 signaling in neurodegeneration research models's disease. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  104. Latif R et al. (2025). Mechanisms in Thyroid Eye Disease: The TSH Receptor Interacts Directly With the IGF-1… [PMID: 39821041]

    Laboratory literature summary: Mechanisms in Thyroid Eye Disease: The TSH Receptor Interacts Directly With the IGF-1 Receptor. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  105. Tentori L et al. (2007). Doping with growth hormone/IGF-1, anabolic steroids or erythropoietin: is there a… [PMID: 17349798]

    Laboratory literature summary: Doping with growth hormone/IGF-1, anabolic steroids or erythropoietin: is there a oncology research models risk?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  106. Wan Y et al. (2022). Role of IGF-1 in neuroinflammation and cognition deficits induced by sleep deprivation [PMID: 35276231]

    Laboratory literature summary: Role of IGF-1 in neuroinflammation and cognition deficits induced by sleep deprivation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  107. Freda PU (2009). Monitoring of acromegaly: what should be performed when GH and IGF-1 levels are… [PMID: 19226264]

    Laboratory literature summary: Monitoring of acromegaly: what should be performed when GH and IGF-1 levels are discrepant?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  108. Ranjan R et al. (2023). IGF-1 stabilizes goat sperm mitochondrial transmembrane potential and reduces dna… [PMID: 38311926]

    Laboratory literature summary: IGF-1 stabilizes goat sperm mitochondrial transmembrane potential and reduces dna fragmentation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  109. Arcopinto M et al. (2013). The GH/IGF-1 axis in chronic heart failure [PMID: 23369140]

    Laboratory literature summary: The GH/IGF-1 axis in chronic heart failure. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  110. Messina M et al. (2018). Does soy protein affect circulating levels of unbound IGF-1? [PMID: 28434035]

    Laboratory literature summary: Does soy protein affect circulating levels of unbound IGF-1?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  111. Sattgast LH et al. (2022). Ethanol alters the relationship between IGF-1 and bone turnover in research models… [PMID: 36194528]

    Laboratory literature summary: Ethanol alters the relationship between IGF-1 and bone turnover in research models macaques. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  112. Kleinberg DL (1997). Early mammary development: growth hormone and IGF-1 [PMID: 10887519]

    Laboratory literature summary: Early mammary development: growth hormone and IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  113. Katic M et al. (2005). The role of insulin and IGF-1 signaling in longevity [PMID: 15723168]

    Laboratory literature summary: The role of insulin and IGF-1 signaling in longevity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  114. Ascenzi F et al. (2019). Effects of IGF-1 isoforms on muscle-biology endpoints and sarcopenia [PMID: 30953403]

    Laboratory literature summary: Effects of IGF-1 isoforms on muscle-biology endpoints and sarcopenia. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  115. Chen S et al. (2018). IGF-1 facilitates thrombopoiesis primarily through Akt activation [PMID: 29802222]

    Laboratory literature summary: IGF-1 facilitates thrombopoiesis primarily through Akt activation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  116. Jiang W et al. (2022). Short communication: TNF-α and IGF-1 regulates epigenetic mechanisms of HDAC2 and HDAC10 [PMID: 35143520]

    Laboratory literature summary: Short communication: TNF-α and IGF-1 regulates epigenetic mechanisms of HDAC2 and HDAC10. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  117. Mäntyselkä A et al. (2019). Associations of IGF-1 and Adrenal Androgens with Cognition in Childhood [PMID: 31401625]

    Laboratory literature summary: Associations of IGF-1 and Adrenal Androgens with Cognition in Childhood. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  118. Maggio M et al. (2013). IGF-1, the cross road of the nutritional, inflammatory and hormonal pathways to frailty [PMID: 24152751]

    Laboratory literature summary: IGF-1, the cross road of the nutritional, inflammatory and hormonal pathways to frailty. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  119. Oldfield EH et al. (2017). Correlation between GH and IGF-1 during investigation for acromegaly [PMID: 27858572]

    Laboratory literature summary: Correlation between GH and IGF-1 during investigation for acromegaly. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  120. Baserga R (2009). Customizing the targeting of IGF-1 receptor [PMID: 19243297]

    Laboratory literature summary: Customizing the targeting of IGF-1 receptor. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  121. Zhao Z et al. (2025). Association of IGF-1 with hypertension among children and adolescents [PMID: 41039295]

    Laboratory literature summary: Association of IGF-1 with hypertension among children and adolescents. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  122. Nagao H et al. (2023). Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling [PMID: 36548088]

    Laboratory literature summary: Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  123. Lu Z et al. (2023). Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris [PMID: 37261455]

    Laboratory literature summary: Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  124. Laron Z et al. (2023). Congenital IGF-1 deficiency protects from oncology research models: lessons from Laron… [PMID: 37343154]

    Laboratory literature summary: Congenital IGF-1 deficiency protects from oncology research models: lessons from Laron syndrome. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  125. Shuang T et al. (2021). Interaction among estrogen-pathway markers, IGF-1, and H2S on smooth muscle cell… [PMID: 33112794]

    Laboratory literature summary: Interaction among estrogen-pathway markers-pathway markers, IGF-1, and H2S on smooth muscle cell proliferation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  126. Fragala MS et al. (2015). Leukocyte IGF-1 receptor expression during muscle recovery [PMID: 24870578]

    Laboratory literature summary: Leukocyte IGF-1 receptor expression during muscle recovery. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  127. Tang BL (2006). SIRT1, neuronal cell survival and the insulin/IGF-1 aging paradox [PMID: 16464659]

    Laboratory literature summary: SIRT1, neuronal cell survival and the insulin/IGF-1 aging paradox. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  128. Yavas A et al. (2024). Antisense Oligonucleotide-Mediated Downregulation of IGFBPs Enhances IGF-1 Signaling [PMID: 38189760]

    Laboratory literature summary: Antisense Oligonucleotide-Mediated Downregulation of IGFBPs Enhances IGF-1 Signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  129. Daftary SS et al. (2005). IGF-1 in the brain as a regulator of reproductive neuroendocrine function [PMID: 15855296]

    Laboratory literature summary: IGF-1 in the brain as a regulator of reproductive neuroendocrine function. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  130. Castro AM et al. (2005). [GH/IGF-1 and oncology research models: what's new in this association] [PMID: 16444368]

    Laboratory literature summary: [GH/IGF-1 and oncology research models: what's new in this association]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  131. Okawa ER et al. (2021). Essential roles of insulin and IGF-1 receptors during embryonic lineage development [PMID: 33453419]

    Laboratory literature summary: Essential roles of insulin and IGF-1 receptors during embryonic lineage development. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  132. Wang Z et al. (2023). STREM2 and GFAP Mediated the Association of IGF-1 Signaling Biomarkers with… [PMID: 36806504]

    Laboratory literature summary: sTREM2 and GFAP Mediated the Association of IGF-1 Signaling Biomarkers with neurodegeneration research models's Disease Pathology. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  133. Awobajo FO et al. (2022). The effect of genistein on IGF-1, PlGF, sFLT-1 and fetoplacental development [PMID: 36063867]

    Laboratory literature summary: The effect of genistein on IGF-1, PlGF, sFLT-1 and fetoplacental development. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  134. Xun Y et al. (2025). KBTBD2 controls bone development by regulating IGF-1 signaling during osteoblast… [PMID: 39562829]

    Laboratory literature summary: KBTBD2 controls bone development by regulating IGF-1 signaling during osteoblast differentiation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  135. El Essawy ES et al. (2023). Rapamycin insensitive regulation of engineered ligament structure and function by IGF-1 [PMID: 37650137]

    Laboratory literature summary: Rapamycin insensitive regulation of engineered ligament structure and function by IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  136. Torres-Aleman I (2000). Serum growth factors and neuroprotective surveillance: focus on IGF-1 [PMID: 11379797]

    Laboratory literature summary: Serum growth factors and neuroprotective surveillance: focus on IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  137. Samarel AM (2002). IGF-1 Overexpression rescues the failing heart [PMID: 11934828]

    Laboratory literature summary: IGF-1 Overexpression rescues the failing heart. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  138. Lu Y et al. (2026). Laboratory research record on IGF-1 LR3 [PMID: 41134344]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  139. van Heemst D et al. (2005). Reduced insulin/IGF-1 signalling and research subjects longevity [PMID: 15771611]

    Laboratory literature summary: Reduced insulin/IGF-1 signalling and research subjects longevity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  140. Vottero A et al. (2013). New aspects of the physiology of the GH-IGF-1 axis [PMID: 23392098]

    Laboratory literature summary: New aspects of the physiology of the GH-IGF-1 axis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  141. Waldbillig RJ et al. (1990). Insulin and IGF-1 binding in chick sclera [PMID: 2162332]

    Laboratory literature summary: Insulin and IGF-1 binding in chick sclera. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  142. Mourkioti F et al. (2005). IGF-1, inflammation and stem cells: interactions during muscle regeneration [PMID: 16109502]

    Laboratory literature summary: IGF-1, inflammation and stem cells: interactions during muscle regeneration. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  143. Rabinovsky ED (2004). The multifunctional role of IGF-1 in peripheral nerve regeneration [PMID: 15072640]

    Laboratory literature summary: The multifunctional role of IGF-1 in peripheral nerve regeneration. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  144. Szczęsny E et al. (2013). Possible contribution of IGF-1 to depressive disorder [PMID: 24553010]

    Laboratory literature summary: Possible contribution of IGF-1 to depressive disorder. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  145. Li G et al. (2023). IGF-1 Microinjection in the Prefrontal Cortex Attenuates Fentanyl-Seeking Behavior in Mice [PMID: 36951642]

    Laboratory literature summary: IGF-1 Microinjection in the Prefrontal Cortex Attenuates Fentanyl-Seeking Behavior in Mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  146. Barberi L et al. (2009). Muscle involvement and IGF-1 signaling in genetic disorders: new investigational… [PMID: 19293573]

    Laboratory literature summary: Muscle involvement and IGF-1 signaling in genetic disorders: new investigational approaches. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  147. Lee H et al. (2021). IGF-1 Upregulates Biglycan and Decorin by Increasing Translation and Reducing ADAMTS5… [PMID: 33573338]

    Laboratory literature summary: IGF-1 Upregulates Biglycan and Decorin by Increasing Translation and Reducing ADAMTS5 Expression. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  148. Zhang BB et al. (2008). [Variational structure and function of products from IGF-1 gene] [PMID: 18819487]

    Laboratory literature summary: [Variational structure and function of products from IGF-1 gene]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  149. Guan J et al. (2009). IGF-1 derived small neuropeptides and analogues: a novel strategy for the development… [PMID: 19438508]

    Laboratory literature summary: IGF-1 derived small neuropeptides and analogues: a novel strategy for the development of pharmaceuticals for neurological conditions. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  150. Mir S et al. (2017). IGF-1 mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 Cascade [PMID: 28607354]

    Laboratory literature summary: IGF-1 mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 Cascade. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  151. Fang F et al. (2022). Unexpected role for IGF-1 in starvation: Maintenance of blood glucose [PMID: 35914126]

    Laboratory literature summary: Unexpected role for IGF-1 in starvation: Maintenance of blood glucose. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  152. Bonifacio A et al. (2017). IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes [PMID: 27734117]

    Laboratory literature summary: IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  153. Papatsoris AG et al. (2005). Novel insights into the implication of the IGF-1 network in prostate oncology research… [PMID: 15694866]

    Laboratory literature summary: Novel insights into the implication of the IGF-1 network in prostate oncology research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  154. O'Neill BT et al. (2016). Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis [PMID: 27525440]

    Laboratory literature summary: Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  155. Lee W et al. (2021). Thermosensitive Hydrogel Harboring CD146/IGF-1 Nanoparticles for Skeletal-Muscle… [PMID: 35006939]

    Laboratory literature summary: Thermosensitive Hydrogel Harboring CD146/IGF-1 Nanoparticles for Skeletal-Muscle Regeneration. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  156. Smolanka IY et al. (2026). Igf-1 in acne pathogenesis and inositol as possible adjuvant investigation of acne [PMID: 42359871]

    Laboratory literature summary: Igf-1 in acne pathogenesis and inositol as possible adjuvant investigation of acne. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  157. Stremming J et al. (2024). Laboratory research record on IGF-1 LR3 [PMID: 38727325]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  158. Chen QQ et al. (2014). Laboratory research record on IGF-1 LR3 [PMID: 24418087]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  159. Ungvari Z et al. (2012). The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances [PMID: 22451468]

    Laboratory literature summary: The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  160. Moreau F et al. (2022). Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural… [PMID: 36335114]

    Laboratory literature summary: Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  161. Ock S et al. (2021). IGF-1 protects against angiotensin II-induced cardiac fibrosis by targeting αSMA [PMID: 34244467]

    Laboratory literature summary: IGF-1 protects against angiotensin II-induced cardiac fibrosis by targeting αSMA. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  162. Cerit ET et al. (2016). DISCORDANCE BETWEEN GH AND IGF-1 LEVELS IN TURKISH ACROMEGALIC research subjects [PMID: 27631850]

    Laboratory literature summary: DISCORDANCE BETWEEN GH AND IGF-1 LEVELS IN TURKISH ACROMEGALIC research subjects. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  163. Grijalva-Avila J et al. (2020). Milk intake and IGF-1 rs6214 polymorphism as protective factors to metabolic research… [PMID: 31530040]

    Laboratory literature summary: Milk intake and IGF-1 rs6214 polymorphism as protective factors to metabolic research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  164. Baserga R (2004). Targeting the IGF-1 receptor: from rags to riches [PMID: 15341972]

    Laboratory literature summary: Targeting the IGF-1 receptor: from rags to riches. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  165. Varkaris A et al. (2013). Ligand-independent activation of MET through IGF-1/IGF-1R signaling [PMID: 23526299]

    Laboratory literature summary: Ligand-independent activation of MET through IGF-1/IGF-1R signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  166. Kim JY et al. (2024). Combinatory Nanovesicle with siRNA-Loaded Extracellular Vesicle and IGF-1 for… [PMID: 38791285]

    Laboratory literature summary: Combinatory Nanovesicle with siRNA-Loaded Extracellular Vesicle and IGF-1 for Osteoarthritis experimental regimens. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  167. Pagani S et al. (2019). GH-IGF-1 Axis in Children with Cystic Fibrosis [PMID: 31462537]

    Laboratory literature summary: GH-IGF-1 Axis in Children with Cystic Fibrosis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  168. Li F et al. (2018). IGF-1 regulates Ang II and VEGF signaling pathways in retinal neovascularization [PMID: 30338783]

    Laboratory literature summary: IGF-1 regulates Ang II and VEGF signaling pathways in retinal neovascularization. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  169. Plummer JD et al. (2022). Intermittent methionine restriction reduces IGF-1 levels and produces similar… [PMID: 35570387]

    Laboratory literature summary: Intermittent methionine restriction reduces IGF-1 levels and produces similar healthspan benefits to continuous methionine restriction. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  170. Shang Y et al. (2020). An Ultrashort Peptide-Based Supramolecular Hydrogel Mimicking IGF-1 to Alleviate… [PMID: 32668906]

    Laboratory literature summary: An Ultrashort Peptide-Based Supramolecular Hydrogel Mimicking IGF-1 to Alleviate Glucocorticoid-Induced Sarcopenia. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  171. Kadri Z et al. (2015). Erythropoietin and IGF-1 signaling synchronize cell proliferation and maturation… [PMID: 26680303]

    Laboratory literature summary: Erythropoietin and IGF-1 signaling synchronize cell proliferation and maturation during erythropoiesis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  172. Musarò A et al. (2007). The neuroprotective effects of a locally acting IGF-1 isoform [PMID: 16782294]

    Laboratory literature summary: The neuroprotective effects of a locally acting IGF-1 isoform. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  173. Nagao H et al. (2021). Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular… [PMID: 33879610]

    Laboratory literature summary: Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  174. Pollak M (2009). Aging, IGF-1, and diet [PMID: 19281498]

    Laboratory literature summary: Aging, IGF-1, and diet. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  175. Yesilkaya UH et al. (2021). Evaluation of IGF-1 as a novel theranostic biomarker for schizophrenia [PMID: 34116443]

    Laboratory literature summary: Evaluation of IGF-1 as a novel theranostic biomarker for schizophrenia. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  176. Ewald CY et al. (2018). Untangling Longevity, Dauer, and Healthspan in Caenorhabditis elegans… [PMID: 28934747]

    Laboratory literature summary: Untangling Longevity, Dauer, and Healthspan in Caenorhabditis elegans Insulin/IGF-1-Signalling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  177. Liu YJ et al. (2013). Expression and significance of IGF-1 and IGF-1R in thyroid nodules [PMID: 23288662]

    Laboratory literature summary: Expression and significance of IGF-1 and IGF-1R in thyroid nodules. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  178. Grinberg YY et al. (2017). Intranasally administered IGF-1 inhibits spreading depression in vivo [PMID: 28951235]

    Laboratory literature summary: Intranasally administered IGF-1 inhibits spreading depression in vivo. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  179. Guo C et al. (2018). IGFBPL1 Regulates Axon Growth through IGF-1-mediated Signaling Cascades [PMID: 29391597]

    Laboratory literature summary: IGFBPL1 Regulates Axon Growth through IGF-1-mediated Signaling Cascades. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  180. Alonso A et al. (2012). Neuroprotective role of estrogens: relationship with insulin/IGF-1 signaling [PMID: 22201898]

    Laboratory literature summary: Neuroprotective role of estrogens: relationship with insulin/IGF-1 signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  181. Kim DJ et al. (2021). IGF-1 Protects Neurons in the Cortex and Subventricular Zone in a Periventricular… [PMID: 33402478]

    Laboratory literature summary: IGF-1 Protects Neurons in the Cortex and Subventricular Zone in a Periventricular Leucomalacia Model. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  182. Jdeed S et al. (2022). The Role of ARID1A in the Nonestrogenic Modulation of IGF-1 Signaling [PMID: 35320351]

    Laboratory literature summary: The Role of ARID1A in the Nonestrogenic Modulation of IGF-1 Signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  183. Shan Y et al. (2022). Laboratory research record on IGF-1 LR3 [PMID: 35297369]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  184. Ogata N et al. (2008). [Involvement of insulin and IGF-1 signaling molecules in bone metabolism] [PMID: 18445879]

    Laboratory literature summary: [Involvement of insulin and IGF-1 signaling molecules in bone metabolism]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  185. Teppala S et al. (2010). Association between IGF-1 and chronic kidney disease among US adults [PMID: 20567872]

    Laboratory literature summary: Association between IGF-1 and chronic kidney disease among US adults. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  186. Blum G et al. (2000). Substrate competitive inhibitors of IGF-1 receptor kinase [PMID: 11123895]

    Laboratory literature summary: Substrate competitive inhibitors of IGF-1 receptor kinase. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  187. Tsugawa Y et al. (2019). Arginine induces IGF-1 secretion from the endoplasmic reticulum [PMID: 31101333]

    Laboratory literature summary: Arginine induces IGF-1 secretion from the endoplasmic reticulum. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  188. Kos S et al. (2019). IGF-1 and IGF-1 SDS – fit for purpose? [PMID: 31505458]

    Laboratory literature summary: IGF-1 and IGF-1 SDS – fit for purpose?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  189. Pelletier JP et al. (1994). [Role of synovial inflammation, cytokines and IGF-1 in the physiopathology of… [PMID: 7858605]

    Laboratory literature summary: [Role of synovial inflammation, cytokines and IGF-1 in the physiopathology of osteoarthritis]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  190. Xiagedeer B et al. (2020). Chlormequat chloride promotes rat embryonic growth and GH-IGF-1 axis [PMID: 31704167]

    Laboratory literature summary: Chlormequat chloride promotes rat embryonic growth and GH-IGF-1 axis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  191. Boosani CS et al. (2025). Hybrid Receptor-Mediated Molecular Delineations in TNF-α and IGF-1-Induced… [PMID: 41155321]

    Laboratory literature summary: Hybrid Receptor-Mediated Molecular Delineations in TNF-α and IGF-1-Induced Costimulatory Effects. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  192. Watamoto Y et al. (2019). IGF-1 regulate the expression of uncoupling protein 2 via FOXO1 [PMID: 32156173]

    Laboratory literature summary: IGF-1 regulate the expression of uncoupling protein 2 via FOXO1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  193. Ballester-Rosado CJ et al. (2025). IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and… [PMID: 39516073]

    Laboratory literature summary: IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  194. Koegelenberg AS et al. (2016). IGF-1 and NT-proBNP in a black and white population: The SABPA study [PMID: 27455178]

    Laboratory literature summary: IGF-1 and NT-proBNP in a black and white population: The SABPA study. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  195. Bioletto F et al. (2025). Central and peripheral regulation of the GH/IGF-1 axis: GHRH and beyond [PMID: 39579280]

    Laboratory literature summary: Central and peripheral regulation of the GH/IGF-1 axis: GHRH and beyond. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  196. Richards JR et al. (2023). Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal… [PMID: 37500798]

    Laboratory literature summary: Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  197. Cai W et al. (2017). Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression [PMID: 28345670]

    Laboratory literature summary: Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  198. Doria PLS et al. (2018). Association of IGF-1 CA(n) and IGFBP3 rs2854746 Polymorphisms with Endometrial Polyp Risk [PMID: 30643822]

    Laboratory literature summary: Association of IGF-1 CA(n) and IGFBP3 rs2854746 Polymorphisms with Endometrial Polyp Risk. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  199. Gazit N et al. (2016). IGF-1 Receptor Differentially Regulates Spontaneous and Evoked Transmission via… [PMID: 26804996]

    Laboratory literature summary: IGF-1 Receptor Differentially Regulates Spontaneous and Evoked Transmission via Mitochondria at Hippocampal Synapses. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  200. Demirel A et al. (2014). Relationships between IGF-1, schizophrenia, and investigation of metabolic syndrome [PMID: 24850069]

    Laboratory literature summary: Relationships between IGF-1, schizophrenia, and investigation of metabolic syndrome. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  201. Lammers R et al. (1989). Differential signalling potential of insulin- and IGF-1-receptor cytoplasmic domains [PMID: 2548842]

    Laboratory literature summary: Differential signalling potential of insulin- and IGF-1-receptor cytoplasmic domains. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  202. LaBelle EF et al. (2004). LDL, IGF-1, and VSMC apoptosis: linking atherogenesis to plaque rupture in vulnerable… [PMID: 14736535]

    Laboratory literature summary: LDL, IGF-1, and VSMC apoptosis: linking atherogenesis to plaque rupture in vulnerable lesions. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  203. Okada K et al. (2017). S-nitrosylation of the IGF-1 receptor disrupts the cell proliferative action of IGF-1 [PMID: 28709872]

    Laboratory literature summary: S-nitrosylation of the IGF-1 receptor disrupts the cell proliferative action of IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  204. LeRoith D et al. (2004). The new kid on the block(ade) of the IGF-1 receptor [PMID: 15050909]

    Laboratory literature summary: The new kid on the block(ade) of the IGF-1 receptor. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  205. Crosby P et al. (2019). Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time [PMID: 31030999]

    Laboratory literature summary: Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  206. Bogin B et al. (2015). Sex, Sport, IGF-1 and the Community Effect in Height Hypothesis [PMID: 25946190]

    Laboratory literature summary: Sex, Sport, IGF-1 and the Community Effect in Height Hypothesis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  207. Chapes SK et al. (1999). Effects of space flight and IGF-1 on immune function [PMID: 11710377]

    Laboratory literature summary: Effects of space flight and IGF-1 on immune function. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  208. Wang H et al. (2019). IGF-1 Promotes Endocytosis of Alveolar Epithelial Cells through PI3K Signaling [PMID: 30814071]

    Laboratory literature summary: IGF-1 Promotes Endocytosis of Alveolar Epithelial Cells through PI3K Signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  209. Ewald CY et al. (2015). Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity [PMID: 25517099]

    Laboratory literature summary: Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  210. Choucair A et al. (2019). The arginine methyltransferase PRMT1 regulates IGF-1 signaling in breast oncology… [PMID: 30692633]

    Laboratory literature summary: The arginine methyltransferase PRMT1 regulates IGF-1 signaling in breast oncology research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  211. Schott M et al. (2004). IGF-1, IGFBP-3, and oncology research models risk [PMID: 15276379]

    Laboratory literature summary: IGF-1, IGFBP-3, and oncology research models risk. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  212. Holly J (2004). IGF-1, IGFBP-3, and oncology research models risk [PMID: 15276380]

    Laboratory literature summary: IGF-1, IGFBP-3, and oncology research models risk. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  213. Musicant AM et al. (2021). CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition [PMID: 33626346]

    Laboratory literature summary: CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  214. Lim SY et al. (2018). Dietary Acid Load, IGF-1 Single Nucleotide Polymorphism and Bone Resorption among… [PMID: 30018240]

    Laboratory literature summary: Dietary Acid Load, IGF-1 Single Nucleotide Polymorphism and Bone Resorption among Postmenopausal Chinese research subjects. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  215. Zhang F et al. (2021). A viral insulin-like peptide is a natural competitive antagonist of the research… [PMID: 34400347]

    Laboratory literature summary: A viral insulin-like peptide is a natural competitive antagonist of the research subjects IGF-1 receptor. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  216. Molinelli A et al. (2010). IGF-1 abuse in sport: laboratory and medico-legal aspects [PMID: 21178942]

    Laboratory literature summary: IGF-1 abuse in sport: laboratory and medico-legal aspects. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  217. Hernandez DM et al. (2020). IPF pathogenesis is dependent upon TGFβ induction of IGF-1 [PMID: 32067272]

    Laboratory literature summary: IPF pathogenesis is dependent upon TGFβ induction of IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  218. Costelli P et al. (2006). IGF-1 is downregulated in experimental oncology research models cachexia [PMID: 16614058]

    Laboratory literature summary: IGF-1 is downregulated in experimental oncology research models cachexia. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  219. Caprio S et al. (2024). Paradoxical effect of dopamine-agonists on IGF-1 in research subjects with… [PMID: 38902646]

    Laboratory literature summary: Paradoxical effect of dopamine-agonists on IGF-1 in research subjects with prolactinoma: the role of weight. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  220. Yakar S et al. (2002). Circulating levels of IGF-1 directly regulate bone growth and density [PMID: 12235108]

    Laboratory literature summary: Circulating levels of IGF-1 directly regulate bone growth and density. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  221. Fazeli PK et al. (2020). IGF-1 is associated with estimated bone strength in anorexia nervosa [PMID: 31656971]

    Laboratory literature summary: IGF-1 is associated with estimated bone strength in anorexia nervosa. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  222. Zhao RL et al. (2019). (p)NNS-Conjugated Chitosan Mediated IGF-1 and miR-140 Overexpression in Articular… [PMID: 31016187]

    Laboratory literature summary: (p)NNS-Conjugated Chitosan Mediated IGF-1 and miR-140 Overexpression in Articular Chondrocytes Improves Cartilage Repair. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  223. Xu H et al. (2025). Expressions of IGF-1, pAKT, and pS6 in Uterosacral Ligaments of research subjects with… [PMID: 40478270]

    Laboratory literature summary: Expressions of IGF-1, pAKT, and pS6 in Uterosacral Ligaments of research subjects with Pelvic Organ Prolapse. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  224. Matar M et al. (2016). The Relationship Between Calciotropic Hormones, IGF-1, and Bone Mass Across Pubertal… [PMID: 27676398]

    Laboratory literature summary: The Relationship Between Calciotropic Hormones, IGF-1, and Bone Mass Across Pubertal Stages. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  225. Chesnokova V et al. (2019). Growth Hormone Induces Colon DNA Damage Independent of IGF-1 [PMID: 31002310]

    Laboratory literature summary: Growth Hormone Induces Colon DNA Damage Independent of IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  226. Reverchon M et al. (2012). Chemerin inhibits IGF-1-induced progesterone and estradiol secretion in research… [PMID: 22447628]

    Laboratory literature summary: Chemerin inhibits IGF-1-induced progesterone and estradiol secretion in research subjects granulosa cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  227. Baserga R et al. (1993). Cell cycle control by the IGF-1 receptor and its ligands [PMID: 8184731]

    Laboratory literature summary: Cell cycle control by the IGF-1 receptor and its ligands. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  228. Song Y et al. (2016). Neuroprotective levels of IGF-1 exacerbate epileptogenesis after brain injury [PMID: 27561791]

    Laboratory literature summary: Neuroprotective levels of IGF-1 exacerbate epileptogenesis after brain injury. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  229. Ni F et al. (2013). IGF-1 promotes the development and cytotoxic activity of research subjects NK cells [PMID: 23403580]

    Laboratory literature summary: IGF-1 promotes the development and cytotoxic activity of research subjects NK cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  230. Nelson DM et al. (2011). Controlled release of IGF-1 and HGF from a biodegradable polyurethane scaffold [PMID: 21347565]

    Laboratory literature summary: Controlled release of IGF-1 and HGF from a biodegradable polyurethane scaffold. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  231. Feng G et al. (2016). IGF-1 C Domain-Modified Hydrogel Enhances Cell research protocol for AKI [PMID: 26869006]

    Laboratory literature summary: IGF-1 C Domain-Modified Hydrogel Enhances Cell research protocol for AKI. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  232. Li Q et al. (2019). Laboratory research record on IGF-1 LR3 [PMID: 31562314]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  233. Larkey NE et al. (2022). Differentiation of Common IGF-1 Variants Using HRMS COM Determination with Follow-Up… [PMID: 36127593]

    Laboratory literature summary: Differentiation of Common IGF-1 Variants Using HRMS COM Determination with Follow-Up MS/MS Verification. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  234. Castilla-Cortázar I et al. (2019). Neurotrophic Factors and Their Receptors Are Altered by the Mere Partial IGF-1 Deficiency [PMID: 30708048]

    Laboratory literature summary: Neurotrophic Factors and Their Receptors Are Altered by the Mere Partial IGF-1 Deficiency. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  235. Hamrick MW et al. (2015). The adipokine leptin mediates muscle- and liver-derived IGF-1 in aged mice [PMID: 26220769]

    Laboratory literature summary: The adipokine leptin mediates muscle- and liver-derived IGF-1 in aged mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  236. Zhang J et al. (2019). Ginsenoside F1 promotes angiogenesis by activating the IGF-1/IGF1R pathway [PMID: 31048033]

    Laboratory literature summary: Ginsenoside F1 promotes angiogenesis by activating the IGF-1/IGF1R pathway. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  237. Tang W et al. (2015). Caveolin-1 Confers Resistance of Hepatoma Cells to Anoikis by Activating IGF-1 Pathway [PMID: 26138883]

    Laboratory literature summary: Caveolin-1 Confers Resistance of Hepatoma Cells to Anoikis by Activating IGF-1 Pathway. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  238. Rosellini E et al. (2021). IGF-1 loaded parenteral-route administration microspheres for potential repair of the… [PMID: 32772783]

    Laboratory literature summary: IGF-1 loaded parenteral-route administration microspheres for potential repair of the infarcted myocardium. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  239. Lara-Diaz VJ et al. (2017). IGF-1 modulates gene expression of proteins involved in inflammation, cytoskeleton,… [PMID: 28124277]

    Laboratory literature summary: IGF-1 modulates gene expression of proteins involved in inflammation, cytoskeleton, and liver architecture. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  240. Narasimhan SD et al. (2009). InAKTivation of insulin/IGF-1 signaling by dephosphorylation [PMID: 19901535]

    Laboratory literature summary: InAKTivation of insulin/IGF-1 signaling by dephosphorylation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  241. Moll L et al. (2016). The inhibition of IGF-1 signaling promotes proteostasis by enhancing protein… [PMID: 26722006]

    Laboratory literature summary: The inhibition of IGF-1 signaling promotes proteostasis by enhancing protein aggregation and deposition. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  242. Franciosi CM et al. (2003). IGF-1 and IGF-1BP3 in gastric adenocarcinoma. Preliminary study [PMID: 12630045]

    Laboratory literature summary: IGF-1 and IGF-1BP3 in gastric adenocarcinoma. Preliminary study. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  243. Mysoet J et al. (2015). Role of IGF-1 in cortical plasticity and functional deficit induced by sensorimotor… [PMID: 25958232]

    Laboratory literature summary: Role of IGF-1 in cortical plasticity and functional deficit induced by sensorimotor restriction. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  244. Jiménez Garduño AM et al. (2017). Altered ionic currents and amelioration by IGF-1 and PACAP in motoneuron-derived cells… [PMID: 28511915]

    Laboratory literature summary: Altered ionic currents and amelioration by IGF-1 and PACAP in motoneuron-derived cells modelling SBMA. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  245. Kappeler L et al. (2008). Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine… [PMID: 18959478]

    Laboratory literature summary: Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  246. Thomas A et al. (2011). Determination of IGF-1 and IGF-2, their degradation products and synthetic analogues… [PMID: 21157622]

    Laboratory literature summary: Determination of IGF-1 and IGF-2, their degradation products and synthetic analogues in urine by LC-MS/MS. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  247. Li D et al. (2014). Hyperplasia and cellularity changes in IGF-1-overexpressing skeletal muscle of crucian… [PMID: 24617525]

    Laboratory literature summary: Hyperplasia and cellularity changes in IGF-1-overexpressing skeletal muscle of crucian carp. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  248. Lekic T et al. (2016). Intranasal IGF-1 Reduced Rat Pup Germinal Matrix Hemorrhage [PMID: 26463950]

    Laboratory literature summary: Intranasal IGF-1 Reduced Rat Pup Germinal Matrix Hemorrhage. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  249. Zou X et al. (2024). IGF-1 rs6218 polymorphisms modulate the susceptibility to age-related cataract [PMID: 38618568]

    Laboratory literature summary: IGF-1 rs6218 polymorphisms modulate the susceptibility to age-related cataract. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  250. De Bruyne E et al. (2010). IGF-1 suppresses Bim expression in multiple myeloma via epigenetic and… [PMID: 20086250]

    Laboratory literature summary: IGF-1 suppresses Bim expression in multiple myeloma via epigenetic and posttranslational mechanisms. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  251. Zylberberg D et al. (2006). [IGF-1 plasma levels evaluation in prolactinoma] [PMID: 17057896]

    Laboratory literature summary: [IGF-1 plasma levels evaluation in prolactinoma]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  252. Lakshmikuttyamma A et al. (2008). Bcr-Abl induces autocrine IGF-1 signaling [PMID: 18246120]

    Laboratory literature summary: Bcr-Abl induces autocrine IGF-1 signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  253. Wang H et al. (2022). A variant rs6214 within IGF-1 confers risk for ulcerative colitis in Chinese Han… [PMID: 36520299]

    Laboratory literature summary: A variant rs6214 within IGF-1 confers risk for ulcerative colitis in Chinese Han populations. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  254. De Magalhaes Filho CD et al. (2017). Laboratory research record on IGF-1 LR3 [PMID: 26762506]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  255. Magee AI et al. (1988). Insulin and IGF-1 receptors contain covalently bound palmitic acid [PMID: 2843552]

    Laboratory literature summary: Insulin and IGF-1 receptors contain covalently bound palmitic acid. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  256. Yakar S et al. (2009). Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and… [PMID: 19257833]

    Laboratory literature summary: Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  257. Hinkal G et al. (2008). How does suppression of IGF-1 signaling by DNA damage affect aging and longevity? [PMID: 18374391]

    Laboratory literature summary: How does suppression of IGF-1 signaling by DNA damage affect aging and longevity?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  258. Doyle SL et al. (2012). IGF-1 and its receptor in esophageal oncology research models: association with… [PMID: 22146489]

    Laboratory literature summary: IGF-1 and its receptor in esophageal oncology research models: association with adenocarcinoma and visceral metabolic research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  259. Kaur N et al. (2025). Uncovering the intricacies of IGF-1 in neurodegeneration research models's disease:… [PMID: 39883327]

    Laboratory literature summary: Uncovering the intricacies of IGF-1 in neurodegeneration research models's disease: new insights from regulation to investigational…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  260. Grunbaum-Novak N et al. (2008). Relationship between antidepressants and IGF-1 system in the brain: possible role in… [PMID: 17961991]

    Laboratory literature summary: Relationship between antidepressants and IGF-1 system in the brain: possible role in cognition. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  261. Hvid H et al. (2013). Investigation with insulin analog X10 and IGF-1 increases growth of colon oncology… [PMID: 24260289]

    Laboratory literature summary: investigation with insulin analog X10 and IGF-1 increases growth of colon oncology research models allografts. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  262. Raval A et al. (2016). Breast oncology research models: Role of IGF-1 and IGFBP-3 expression in prognostication [PMID: 30084561]

    Laboratory literature summary: Breast oncology research models: Role of IGF-1 and IGFBP-3 expression in prognostication. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  263. Kondo T et al. (2003). Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against… [PMID: 12813019]

    Laboratory literature summary: Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  264. Grizard G (1994). [IGF(s) and testicular functions. Secretion and action of IGF-1 on Leydig cells] [PMID: 7994317]

    Laboratory literature summary: [IGF(s) and testicular functions. Secretion and action of IGF-1 on Leydig cells]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  265. Tian YG et al. (2014). Single-nucleotide polymorphism analysis of GH, GHR, and IGF-1 genes in minipigs [PMID: 25098617]

    Laboratory literature summary: Single-nucleotide polymorphism analysis of GH, GHR, and IGF-1 genes in minipigs. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  266. Matsumura S et al. (2017). IGF-1 Mediates EphrinB1 Activation in Regulating Tertiary Dentin Formation [PMID: 28489485]

    Laboratory literature summary: IGF-1 Mediates EphrinB1 Activation in Regulating Tertiary Dentin Formation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  267. Shigematsu S et al. (1999). IGF-1 regulates migration and angiogenesis of research subjects endothelial cells [PMID: 12054122]

    Laboratory literature summary: IGF-1 regulates migration and angiogenesis of research subjects endothelial cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  268. Toth P et al. (2014). IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice [PMID: 25248835]

    Laboratory literature summary: IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  269. Singh K et al. (2015). Superoxide anion radicals induce IGF-1 resistance through concomitant activation of… [PMID: 25520316]

    Laboratory literature summary: Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  270. Zerti D et al. (2021). IGFBPs mediate IGF-1's functions in retinal lamination and photoreceptor development… [PMID: 33442906]

    Laboratory literature summary: IGFBPs mediate IGF-1's functions in retinal lamination and photoreceptor development during pluripotent stem cell differentiation to…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  271. Singh-Mallah G et al. (2017). Cyclic-glycine-proline accelerates mammary involution by promoting apoptosis and… [PMID: 28063218]

    Laboratory literature summary: Cyclic-glycine-proline accelerates mammary involution by promoting apoptosis and inhibiting IGF-1 function. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  272. Rahnama S et al. (2021). Effects of insulin on IGF-1 receptors in equine lamellar tissue in vitro [PMID: 32818904]

    Laboratory literature summary: Effects of insulin on IGF-1 receptors in equine lamellar tissue in vitro. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  273. van Drielen K et al. (2015). Disentangling the effects of circulating IGF-1, glucose, and cortisol on features of… [PMID: 25874752]

    Laboratory literature summary: Disentangling the effects of circulating IGF-1, glucose, and cortisol on features of perceived age. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  274. Teng L et al. (2025). Microbial Lipopolysaccharide Regulates Host Development Through Insulin/IGF-1 Signaling [PMID: 40806528]

    Laboratory literature summary: Microbial Lipopolysaccharide Regulates Host Development Through Insulin/IGF-1 Signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  275. Hoa N et al. (2012). Nuclear targeting of IGF-1 receptor in orbital fibroblasts from Graves' disease:… [PMID: 22506015]

    Laboratory literature summary: Nuclear targeting of IGF-1 receptor in orbital fibroblasts from Graves' disease: apparent role of ADAM17. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  276. Sansone L et al. (2013). SIRT1 silencing confers neuroprotection through IGF-1 pathway activation [PMID: 23359486]

    Laboratory literature summary: SIRT1 silencing confers neuroprotection through IGF-1 pathway activation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  277. Faxén UL et al. (2017). HFpEF and HFrEF Display Different Phenotypes as Assessed by IGF-1 and IGFBP-1 [PMID: 27327968]

    Laboratory literature summary: HFpEF and HFrEF Display Different Phenotypes as Assessed by IGF-1 and IGFBP-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  278. Vinciguerra M et al. (2009). Local IGF-1 isoform protects cardiomyocytes from hypertrophic and oxidative stresses… [PMID: 20228935]

    Laboratory literature summary: Local IGF-1 isoform protects cardiomyocytes from hypertrophic and oxidative stresses via SirT1 activity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  279. Karamouzis MV et al. (2006). The IGF-1 network in lung carcinoma therapeutics [PMID: 17055338]

    Laboratory literature summary: The IGF-1 network in lung carcinoma therapeutics. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  280. Sculthorpe N et al. (2012). Androgens affect myogenesis in vitro and increase local IGF-1 expression [PMID: 21946153]

    Laboratory literature summary: Androgens affect myogenesis in vitro and increase local IGF-1 expression. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  281. Hannon AM et al. (2019). Developmental research context in acromegaly is laboratory profile and is associated… [PMID: 30620709]

    Laboratory literature summary: developmental research context in acromegaly is laboratory profile and is associated with improvements in IGF-1 concentrations. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  282. Honda H et al. (2010). Expression of HGF and IGF-1 during regeneration of masseter muscle in mdx mice [PMID: 20508974]

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  283. García-Marchena N et al. (2017). Decreased plasma concentrations of BDNF and IGF-1 in abstinent research subjects with… [PMID: 29108028]

    Laboratory literature summary: Decreased plasma concentrations of BDNF and IGF-1 in abstinent research subjects with alcohol use disorders. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  284. MacEwen EG et al. (2004). IGF-1 receptor contributes to the malignant phenotype in research subjects and canine… [PMID: 15095405]

    Laboratory literature summary: IGF-1 receptor contributes to the malignant phenotype in research subjects and canine oncology research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  285. Travascio F et al. (2014). Modeling the role of IGF-1 on extracellular matrix biosynthesis and cellularity in… [PMID: 24856835]

    Laboratory literature summary: Modeling the role of IGF-1 on extracellular matrix biosynthesis and cellularity in intervertebral disc. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  286. Hung CF et al. (2013). Role of IGF-1 pathway in lung fibroblast activation [PMID: 24103846]

    Laboratory literature summary: Role of IGF-1 pathway in lung fibroblast activation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  287. Toth P et al. (2015). IGF-1 deficiency impairs neurovascular coupling in mice: implications for… [PMID: 26172407]

    Laboratory literature summary: IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  288. Aghdam SY et al. (2012). Vascular endothelial insulin/IGF-1 signaling controls skin wound vascularization [PMID: 22503682]

    Laboratory literature summary: Vascular endothelial insulin/IGF-1 signaling controls skin wound vascularization. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  289. Ueki K (2009). [The mechanisms whereby insulin/IGF-1 signaling regulates aging and longevity] [PMID: 19591278]

    Laboratory literature summary: [The mechanisms whereby insulin/IGF-1 signaling regulates aging and longevity]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  290. Siler-Khodr TM et al. (1993). Effect of IGF-1 on placental prostanoid production [PMID: 8248549]

    Laboratory literature summary: Effect of IGF-1 on placental prostanoid production. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  291. Krieger CC et al. (2015). Bidirectional TSH and IGF-1 receptor cross talk mediates stimulation of hyaluronan… [PMID: 25485727]

    Laboratory literature summary: Bidirectional TSH and IGF-1 receptor cross talk mediates stimulation of hyaluronan secretion by Graves' disease immunoglobins. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  292. Chen H et al. (2014). Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in… [PMID: 24878056]

    Laboratory literature summary: Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  293. Annibalini G et al. (2018). The intrinsically disordered E-domains regulate the IGF-1 prohormones stability,… [PMID: 29891966]

    Laboratory literature summary: The intrinsically disordered E-domains regulate the IGF-1 prohormones stability, subcellular localisation and secretion. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  294. Obukowicz MG et al. (1988). Secretion and export of IGF-1 in Escherichia coli strain JM101 [PMID: 3071740]

    Laboratory literature summary: Secretion and export of IGF-1 in Escherichia coli strain JM101. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  295. Roitenberg N et al. (2018). Modulation of caveolae by insulin/IGF-1 signaling regulates aging of Caenorhabditis… [PMID: 29945933]

    Laboratory literature summary: Modulation of caveolae by insulin/IGF-1 signaling regulates aging of Caenorhabditis elegans. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  296. Demir AN et al. (2025). Dynamic changes in IGF-1 levels during cabergoline research protocol in prolactinoma [PMID: 41108835]

    Laboratory literature summary: Dynamic changes in IGF-1 levels during cabergoline research protocol in prolactinoma. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  297. Yao J et al. (2017). The effects of IGF-1 on mouse spermatogenesis using an organ culture method [PMID: 28552527]

    Laboratory literature summary: The effects of IGF-1 on mouse spermatogenesis using an organ culture method. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  298. Adams GR et al. (1996). The relationships among IGF-1, DNA content, and protein accumulation during skeletal… [PMID: 9018499]

    Laboratory literature summary: The relationships among IGF-1, DNA content, and protein accumulation during skeletal muscle hypertrophy. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  299. Maugeri G et al. (2022). Emerging Roles of the Neurotrophic Peptides IGF-1 and PACAP in Amyotrophic Lateral… [PMID: 35929635]

    Laboratory literature summary: Emerging Roles of the Neurotrophic Peptides IGF-1 and PACAP in Amyotrophic Lateral Sclerosis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  300. Bjersing JL et al. (2013). Exercise and metabolic research models in fibromyalgia: beneficial roles of IGF-1 and… [PMID: 23446104]

    Laboratory literature summary: Exercise and metabolic research models in fibromyalgia: beneficial roles of IGF-1 and resistin?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  301. Salie R et al. (2005). IGF-1 and BDNF promote chick bulbospinal neurite outgrowth in vitro [PMID: 16143487]

    Laboratory literature summary: IGF-1 and BDNF promote chick bulbospinal neurite outgrowth in vitro. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  302. Smith LM et al. (2004). EphA3 is induced by CD28 and IGF-1 and regulates cell adhesion [PMID: 14697337]

    Laboratory literature summary: EphA3 is induced by CD28 and IGF-1 and regulates cell adhesion. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  303. Papanikolaou T et al. (2009). IGF-1: elixir for motor neuron diseases [PMID: 19679066]

    Laboratory literature summary: IGF-1: elixir for motor neuron diseases. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  304. Fung CM et al. (2015). IUGR prevents IGF-1 upregulation in juvenile research models mice by perturbing… [PMID: 25826117]

    Laboratory literature summary: IUGR prevents IGF-1 upregulation in juvenile research models mice by perturbing postnatal IGF-1 chromatin remodeling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  305. Dahiya S et al. (2018). Unilateral IGF-1 parenteral-route administration for mandibular asymmetry [PMID: 30268251]

    Laboratory literature summary: Unilateral IGF-1 parenteral-route administration for mandibular asymmetry. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  306. Cohen E et al. (2010). Temporal requirements of insulin/IGF-1 signaling for proteotoxicity protection [PMID: 20003171]

    Laboratory literature summary: Temporal requirements of insulin/IGF-1 signaling for proteotoxicity protection. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  307. Hikage F et al. (2025). Effects of linsitinib on M22 and IGF:1-studied 3D spheroids of research subjects… [PMID: 39747159]

    Laboratory literature summary: Effects of linsitinib on M22 and IGF:1-studied 3D spheroids of research subjects orbital fibroblasts. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  308. Akirov A et al. (2018). IGF-1 levels may increase paradoxically with dopamine agonist investigation for… [PMID: 29728863]

    Laboratory literature summary: IGF-1 levels may increase paradoxically with dopamine agonist investigation for prolactinomas. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  309. He J et al. (2019). Upregulated IGF‑1 in the lungs of asthmatic mice originates from alveolar macrophages [PMID: 30535455]

    Laboratory literature summary: Upregulated IGF‑1 in the lungs of asthmatic mice originates from alveolar macrophages. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  310. Yu XY et al. (2008). Glucose induces apoptosis of cardiomyocytes via microRNA-1 and IGF-1 [PMID: 18801338]

    Laboratory literature summary: Glucose induces apoptosis of cardiomyocytes via microRNA-1 and IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  311. Majchrzak-Baczmańska D et al. (2018). Does IGF-1 play a role in the biology of ovarian oncology research models? [PMID: 29411341]

    Laboratory literature summary: Does IGF-1 play a role in the biology of ovarian oncology research models?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  312. Hara M et al. (2014). Relation between circulating levels of GH, IGF-1, ghrelin and somatic growth in Rett… [PMID: 24377437]

    Laboratory literature summary: Relation between circulating levels of GH, IGF-1, ghrelin and somatic growth in Rett syndrome. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  313. Di Biase N et al. (1997). Laboratory research record on IGF-1 LR3 [PMID: 9542266]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  314. Sell C et al. (1993). IGF-1 receptor levels and the proliferation of young and senescent research subjects… [PMID: 7687431]

    Laboratory literature summary: IGF-1 receptor levels and the proliferation of young and senescent research subjects fibroblasts. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  315. Galvin CD et al. (2003). IGF-1 receptor mediates differentiation of primary cultures of mouse skeletal myoblasts [PMID: 12644296]

    Laboratory literature summary: IGF-1 receptor mediates differentiation of primary cultures of mouse skeletal myoblasts. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

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    Laboratory literature summary: The role of IGF-1 and ghrelin in the compensation of intrauterine growth restriction. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

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    Laboratory literature summary: Role of heterotrimeric G protein and calcium in cardiomyocyte hypertrophy induced by IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

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    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

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    Laboratory literature summary: Effects of norepinephrine on expression of IGF-1/IGF-1R and SERCA2 in rat heart. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  320. Cox HD et al. (2014). Sensitive quantification of IGF-1 and its synthetic analogs in dried blood spots [PMID: 25411707]

    Laboratory literature summary: Sensitive quantification of IGF-1 and its synthetic analogs in dried blood spots. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  321. Morales MP et al. (2000). IGF-1 regulates apoptosis of cardiac myocyte induced by osmotic-stress [PMID: 10772945]

    Laboratory literature summary: IGF-1 regulates apoptosis of cardiac myocyte induced by osmotic-stress. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  322. Ock S et al. (2016). Deletion of IGF-1 Receptors in Cardiomyocytes Attenuates Cardiac Aging in research… [PMID: 26469138]

    Laboratory literature summary: Deletion of IGF-1 Receptors in Cardiomyocytes Attenuates Cardiac Aging in research models Mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  323. Liu L et al. (2010). Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway [PMID: 20485667]

    Laboratory literature summary: Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  324. Ayadi AE et al. (2016). IGF-1 protects dopamine neurons against oxidative stress: association with changes in… [PMID: 26894890]

    Laboratory literature summary: IGF-1 protects dopamine neurons against oxidative stress: association with changes in phosphokinases. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  325. Guan J et al. (2014). Cyclic glycine-proline regulates IGF-1 homeostasis by altering the binding of IGFBP-3… [PMID: 24633053]

    Laboratory literature summary: Cyclic glycine-proline regulates IGF-1 homeostasis by altering the binding of IGFBP-3 to IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  326. Yuan H et al. (2015). The regulatory mechanism of neurogenesis by IGF-1 in adult mice [PMID: 24777577]

    Laboratory literature summary: The regulatory mechanism of neurogenesis by IGF-1 in adult mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  327. Rozing MP et al. (2009). Research subjects insulin/IGF-1 and familial longevity at middle age [PMID: 20157552]

    Laboratory literature summary: research subjects insulin/IGF-1 and familial longevity at middle age. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  328. Yu X et al. (2012). IGF-1 alleviates ox-LDL-induced inflammation via reducing HMGB1 release in HAECs [PMID: 22782142]

    Laboratory literature summary: IGF-1 alleviates ox-LDL-induced inflammation via reducing HMGB1 release in HAECs. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  329. Kadakia R et al. (2016). Neonatal adiposity increases with rising cord blood IGF-1 levels [PMID: 26945928]

    Laboratory literature summary: Neonatal adiposity increases with rising cord blood IGF-1 levels. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  330. Jendraschak E et al. (1998). IGF-1, PDGF and CD18 are adherence-responsive genes: regulation during monocyte… [PMID: 9545592]

    Laboratory literature summary: IGF-1, PDGF and CD18 are adherence-responsive genes: regulation during monocyte differentiation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  331. Yalcin O et al. (2026). The effect of IGF-1 on the closure process of processus vaginalis [PMID: 41486112]

    Laboratory literature summary: The effect of IGF-1 on the closure process of processus vaginalis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  332. Lin J et al. (2014). The copy number and integration site analysis of IGF-1 transgenic goat [PMID: 25018125]

    Laboratory literature summary: The copy number and integration site analysis of IGF-1 transgenic goat. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  333. Shirakawa J et al. (2020). Luseogliflozin increases beta cell proliferation through humoral factors that activate… [PMID: 31897526]

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  334. Han Y et al. (2021). Mechanism underlying the stimulation by IGF-1 of LHCGR expression in porcine granulosa… [PMID: 33933758]

    Laboratory literature summary: Mechanism underlying the stimulation by IGF-1 of LHCGR expression in porcine granulosa cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  335. Bjersing JL et al. (2017). Benefits of resistance exercise in lean research subjects with fibromyalgia:… [PMID: 28288611]

    Laboratory literature summary: Benefits of resistance exercise in lean research subjects with fibromyalgia: involvement of IGF-1 and leptin. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  336. Feng R et al. (2015). Positive effect of IGF-1 parenteral-route administration on gastrocnemius of rat… [PMID: 25452218]

    Laboratory literature summary: Positive effect of IGF-1 parenteral-route administration on gastrocnemius of rat during distraction osteogenesis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  337. Chen J et al. (2012). Serum response factor regulates bone formation via IGF-1 and Runx2 signals [PMID: 22434656]

    Laboratory literature summary: Serum response factor regulates bone formation via IGF-1 and Runx2 signals. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

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    Laboratory literature summary: Mechanism of activation of protein kinase B by insulin and IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  339. De Wolf E et al. (1996). Solution structure of a mini IGF-1 [PMID: 8931138]

    Laboratory literature summary: Solution structure of a mini IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

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    Laboratory literature summary: Insulin regulates SOCS2 expression and the mitogenic effect of IGF-1 in mesangial cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  341. Cohen E et al. (2009). Reduced IGF-1 signaling delays age-associated proteotoxicity in mice [PMID: 20005808]

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    Laboratory literature summary: Shared pathways of osteoblast mitogenesis induced by amylin, adrenomedullin, and IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

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    Laboratory literature summary: Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

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    Laboratory literature summary: Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  345. Yoshida S et al. (2015). The minimum peptides of IGF-1 and substance P protect vestibular hair cells against… [PMID: 25739461]

    Laboratory literature summary: The minimum peptides of IGF-1 and substance P protect vestibular hair cells against neomycin ototoxicity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

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    Laboratory literature summary: Epidermal insulin/IGF-1 signalling control interfollicular morphogenesis and proliferative potential through Rac activation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

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    Laboratory literature summary: Involvement of IGF-1/IGFBP-3 signaling on the conspicuousness of facial pores. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  348. Jacquemin V et al. (2004). IGF-1 induces research subjects myotube hypertrophy by increasing cell recruitment [PMID: 15302582]

    Laboratory literature summary: IGF-1 induces research subjects myotube hypertrophy by increasing cell recruitment. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  349. Lowe WL Jr et al. (1986). Tyrosine kinase activity of brain insulin and IGF-1 receptors [PMID: 3004453]

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  350. Holzenberger M (2009). [IGF-1 receptors in the brain control longevity in mice] [PMID: 19409189]

    Laboratory literature summary: [IGF-1 receptors in the brain control longevity in mice]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  351. Skottner A et al. (1986). Experimental research on IGF-1 [PMID: 3473891]

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    Laboratory literature summary: EEN regulates the proliferation and survival of multiple myeloma cells by potentiating IGF-1 secretion. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

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    Laboratory literature summary: Secreted IGFBP5 mediates mTORC1-dependent feedback inhibition of IGF-1 signalling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  354. Reed BY et al. (1995). Serum IGF 1 is low and correlated with osteoblastic surface in idiopathic osteoporosis [PMID: 8585426]

    Laboratory literature summary: Serum IGF 1 is low and correlated with osteoblastic surface in idiopathic osteoporosis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  355. Matsuo R et al. (2008). Platelets Strongly Induce Hepatocyte Proliferation with IGF-1 and HGF In Vitro [PMID: 17688880]

    Laboratory literature summary: Platelets Strongly Induce Hepatocyte Proliferation with IGF-1 and HGF In Vitro. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  356. Brown-Borg HM (2022). Growth Hormone, Not IGF-1 Is the Key Longevity Regulator in Mammals [PMID: 35436323]

    Laboratory literature summary: Growth Hormone, Not IGF-1 Is the Key Longevity Regulator in Mammals. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

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    Laboratory literature summary: Nitric oxide mediates the survival action of IGF-1 and insulin in pancreatic beta cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  358. Hashizume A et al. (2018). IGF-1 for spinal and bulbar muscular atrophy: hope and challenges [PMID: 30337274]

    Laboratory literature summary: IGF-1 for spinal and bulbar muscular atrophy: hope and challenges. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  359. Ly HJ et al. (2024). Interpreting IGF-1 in children studied with recombinant growth hormone: challenges… [PMID: 39906034]

    Laboratory literature summary: Interpreting IGF-1 in children studied with recombinant growth hormone: challenges during early puberty. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

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    Laboratory literature summary: IGF-1 induces foam cell formation in rat glomerular mesangial cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  361. Gong Z et al. (2014). Reductions in serum IGF-1 during aging impair health span [PMID: 24341939]

    Laboratory literature summary: Reductions in serum IGF-1 during aging impair health span. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  362. Khan RS et al. (2014). Targeting extracellular DNA to deliver IGF-1 to the injured heart [PMID: 24604065]

    Laboratory literature summary: Targeting extracellular DNA to deliver IGF-1 to the injured heart. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  363. Kotani K et al. (1994). Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling [PMID: 8194523]

    Laboratory literature summary: Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  364. Jones MR et al. (2012). Zcchc11 uridylates mature miRNAs to enhance neonatal IGF-1 expression, growth, and… [PMID: 23209448]

    Laboratory literature summary: Zcchc11 uridylates mature miRNAs to enhance neonatal IGF-1 expression, growth, and survival. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  365. Jóźków P et al. (2009). [Growth hormone and IGF-1 as doping agents in competitive sport] [PMID: 19885810]

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  366. Orskov H et al. (1993). IGF-1 and acute renal hypertrophy: inhibition by somatostatin analogues [PMID: 8097067]

    Laboratory literature summary: IGF-1 and acute renal hypertrophy: inhibition by somatostatin analogues. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  367. Kim I et al. (2008). Autocrine function of erythropoietin in IGF-1-induced erythropoietin biosynthesis [PMID: 18841090]

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  368. Zoppini G et al. (1994). Phosphotyrosine protein profiles in monocytes after insulin and IGF-1 stimulation [PMID: 8050456]

    Laboratory literature summary: Phosphotyrosine protein profiles in monocytes after insulin and IGF-1 stimulation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  369. Murray SA et al. (2003). IGF-1 activates p21 to inhibit UV-induced cell death [PMID: 12642873]

    Laboratory literature summary: IGF-1 activates p21 to inhibit UV-induced cell death. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  370. Schieber AM et al. (2015). Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling [PMID: 26516283]

    Laboratory literature summary: Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  371. Wang J et al. (2026). IGF-1 regulates PEAR1 through Egr1 to promote skeletal muscle post-injury regeneration [PMID: 41506419]

    Laboratory literature summary: IGF-1 regulates PEAR1 through Egr1 to promote skeletal muscle post-injury regeneration. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  372. Ma X et al. (2012). IGF-1 activates the P13K/AKT signaling pathway via upregulation of secretory clusterin [PMID: 23027041]

    Laboratory literature summary: IGF-1 activates the P13K/AKT signaling pathway via upregulation of secretory clusterin. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  373. Isenović E et al. (2001). Role of PI3-kinase in isoproterenol and IGF-1 induced ecNOS activity [PMID: 11467844]

    Laboratory literature summary: Role of PI3-kinase in isoproterenol and IGF-1 induced ecNOS activity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  374. Mihăescu GF et al. (2006). Is IGF-1 involved in the regulatory modifications of cholesterolemia following the… [PMID: 18386621]

    Laboratory literature summary: Is IGF-1 involved in the regulatory modifications of cholesterolemia following the administration of embryonary peptides?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  375. Bilge M et al. (2015). Assessment of follicular and serum VEGF and IGF-1 in ICSI research subjects: hMG vs rFSH [PMID: 26524801]

    Laboratory literature summary: Assessment of follicular and serum VEGF and IGF-1 in ICSI research subjects: hMG vs rFSH. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  376. Isaksson E et al. (1999). Expression of sex steroid receptors and IGF-1 mRNA in breast tissue–effects of… [PMID: 10622416]

    Laboratory literature summary: Expression of sex steroid receptors and IGF-1 mRNA in breast tissue–effects of hormonal investigation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  377. Bou Khalil R (2011). Recombinant research subjects IGF-1 for research subjects with schizophrenia [PMID: 21703772]

    Laboratory literature summary: Recombinant research subjects IGF-1 for research subjects with schizophrenia. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  378. Nagasao J et al. (2004). Expression of nestin and IGF-1 in rat pancreas after streptozotocin administration [PMID: 15027954]

    Laboratory literature summary: Expression of nestin and IGF-1 in rat pancreas after streptozotocin administration. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  379. Xiao W et al. (2013). Overload training inhibits phagocytosis and ROS generation of peritoneal macrophages:… [PMID: 22592456]

    Laboratory literature summary: Overload training inhibits phagocytosis and ROS generation of peritoneal macrophages: role of IGF-1 and MGF. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  380. Stout GJ et al. (2013). Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism [PMID: 23820781]

    Laboratory literature summary: Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  381. Tseretopoulou X et al. (2020). How to interpret IGF-1 and growth hormone stimulation tests [PMID: 32371419]

    Laboratory literature summary: How to interpret IGF-1 and growth hormone stimulation tests. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  382. Cao XR et al. (2008). Nedd4 controls animal growth by regulating IGF-1 signaling [PMID: 18812566]

    Laboratory literature summary: Nedd4 controls animal growth by regulating IGF-1 signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  383. Cekmez F et al. (2012). Correlation between cord blood apelin and IGF-1 levels in retinopathy of prematurity [PMID: 23227848]

    Laboratory literature summary: Correlation between cord blood apelin and IGF-1 levels in retinopathy of prematurity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  384. Palazzolo I et al. (2009). Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and… [PMID: 19679072]

    Laboratory literature summary: Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  385. Mantripragada VP et al. (2014). IGF-1 release kinetics from chitosan microparticles fabricated using environmentally… [PMID: 25063148]

    Laboratory literature summary: IGF-1 release kinetics from chitosan microparticles fabricated using environmentally benign conditions. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  386. Maher F et al. (1990). Stabilization of glucose transporter mRNA by insulin/IGF-1 and glucose deprivation [PMID: 2168170]

    Laboratory literature summary: Stabilization of glucose transporter mRNA by insulin/IGF-1 and glucose deprivation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  387. Lo MY et al. (2004). Chondrocyte apoptosis induced by collagen degradation: inhibition by caspase… [PMID: 14656672]

    Laboratory literature summary: Chondrocyte apoptosis induced by collagen degradation: inhibition by caspase inhibitors and IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  388. Burchardt P et al. (2010). Are elevated levels of IGF-1 caused by coronary arteriesoclerosis?: Molecular and… [PMID: 21046444]

    Laboratory literature summary: Are elevated levels of IGF-1 caused by coronary arteriesoclerosis?: Molecular and laboratory analysis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  389. Vaira V et al. (2007). Regulation of survivin expression by IGF-1/mTOR signaling [PMID: 17072337]

    Laboratory literature summary: Regulation of survivin expression by IGF-1/mTOR signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  390. Korulu S et al. (2011). IGF-1 participates differently in regulation of severing activity of katanin and spastin [PMID: 21274617]

    Laboratory literature summary: IGF-1 participates differently in regulation of severing activity of katanin and spastin. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  391. Tellatin S et al. (2018). Coronary microvascular dysfunction may be related to IGF-1 in acromegalic research… [PMID: 29353224]

    Laboratory literature summary: Coronary microvascular dysfunction may be related to IGF-1 in acromegalic research subjects and can be restored by research protocol. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  392. Slawik M et al. (2006). Investigation with insulin glargine does not suppress serum IGF-1 [PMID: 16842489]

    Laboratory literature summary: investigation with insulin glargine does not suppress serum IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  393. Bhavsar PK et al. (2010). Clenbuterol induces cardiac myocyte hypertrophy via paracrine signalling and… [PMID: 20577844]

    Laboratory literature summary: Clenbuterol induces cardiac myocyte hypertrophy via paracrine signalling and fibroblast-derived IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  394. Brownell D et al. (2026). IGF-1 Increases Collagen Deposition by Dermal Fibroblasts: Applications for Tissue… [PMID: 42274614]

    Laboratory literature summary: IGF-1 Increases Collagen Deposition by Dermal Fibroblasts: Applications for Tissue Engineering. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  395. Berfield AK et al. (2006). IGF-1 induces rat glomerular mesangial cells to accumulate triglyceride [PMID: 16077083]

    Laboratory literature summary: IGF-1 induces rat glomerular mesangial cells to accumulate triglyceride. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  396. Wass JA (1993). Actual and potential laboratory uses of IGF-1 [PMID: 7921001]

    Laboratory literature summary: Actual and potential laboratory uses of IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  397. Qa'aty N et al. (2015). Synthetic ligands of the elastin receptor induce elastogenesis in research subjects… [PMID: 26475432]

    Laboratory literature summary: Synthetic ligands of the elastin receptor induce elastogenesis in research subjects dermal fibroblasts via activation of their IGF-1…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  398. Dillin A et al. (2002). Timing requirements for insulin/IGF-1 signaling in C. elegans [PMID: 12399591]

    Laboratory literature summary: Timing requirements for insulin/IGF-1 signaling in C. elegans. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  399. Zygar CA et al. (2005). IGF-1 produced by cone photoreceptors regulates rod progenitor proliferation in the… [PMID: 15617759]

    Laboratory literature summary: IGF-1 produced by cone photoreceptors regulates rod progenitor proliferation in the teleost retina. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  400. Franklin L et al. (2006). The effects of IGF-1 on cellular phospholipids [PMID: 16817585]

    Laboratory literature summary: The effects of IGF-1 on cellular phospholipids. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  401. Carlsson-Skwirut C et al. (1986). Isolation and characterization of variant IGF-1 as well as IGF-2 from adult research… [PMID: 3709807]

    Laboratory literature summary: Isolation and characterization of variant IGF-1 as well as IGF-2 from adult research subjects brain. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  402. Maya-Vetencourt JF et al. (2012). IGF-1 restores visual cortex plasticity in adult life by reducing local GABA levels [PMID: 22720172]

    Laboratory literature summary: IGF-1 restores visual cortex plasticity in adult life by reducing local GABA levels. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  403. Grubb A et al. (2014). IGF-1 colocalizes with muscle satellite cells following acute exercise in research… [PMID: 24669996]

    Laboratory literature summary: IGF-1 colocalizes with muscle satellite cells following acute exercise in research subjects. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  404. Berwert L et al. (1995). Ontogeny of IGF-1 and the classical islet hormones in the turbot, Scophthalmus maximus [PMID: 7716063]

    Laboratory literature summary: Ontogeny of IGF-1 and the classical islet hormones in the turbot, Scophthalmus maximus. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  405. Mu L et al. (2012). Favorable outcome associated with an IGF-1 ligand signature in breast oncology… [PMID: 22297468]

    Laboratory literature summary: Favorable outcome associated with an IGF-1 ligand signature in breast oncology research models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  406. Xu X et al. (2008). Delivery of plasmid IGF-1 to chondrocytes via cationized gelatin nanoparticles [PMID: 17600330]

    Laboratory literature summary: Delivery of plasmid IGF-1 to chondrocytes via cationized gelatin nanoparticles. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  407. Lowman HB et al. (1998). Molecular mimics of insulin-like growth factor 1 (IGF-1) for inhibiting IGF-1:… [PMID: 9636028]

    Laboratory literature summary: Molecular mimics of insulin-like growth factor 1 (IGF-1) for inhibiting IGF-1: IGF-binding protein interactions. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  408. Xian L et al. (2012). Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells [PMID: 22729283]

    Laboratory literature summary: Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  409. Hejnaes KR et al. (1992). Development of an optimized refolding process for recombinant Ala-Glu-IGF-1 [PMID: 1287661]

    Laboratory literature summary: Development of an optimized refolding process for recombinant Ala-Glu-IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  410. Tashiro T et al. (1999). Effect of IGF-1 on protein metabolism in burned rats [PMID: 10483905]

    Laboratory literature summary: Effect of IGF-1 on protein metabolism in burned rats. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  411. Chesik D et al. (2008). IGF-1 regulates cAMP levels in astrocytes through a beta2-adrenergic… [PMID: 18690292]

    Laboratory literature summary: IGF-1 regulates cAMP levels in astrocytes through a beta2-adrenergic receptor-dependant mechanism. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  412. Vanderhoof JA (1996). Results of IGF-1 studies show promise in the investigation of intestinal disorders [PMID: 8887897]

    Laboratory literature summary: Results of IGF-1 studies show promise in the investigation of intestinal disorders. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  413. Inishi Y et al. (1997). Modulation of renal hemodynamics by IGF-1 is absent in spontaneously hypertensive rats [PMID: 9211359]

    Laboratory literature summary: Modulation of renal hemodynamics by IGF-1 is absent in spontaneously hypertensive rats. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  414. Zhai J et al. (2025). The effect of modulation Piezo2 by IGF-1 on tactile hypersensitivity in BTBR model mice [PMID: 39920984]

    Laboratory literature summary: The effect of modulation Piezo2 by IGF-1 on tactile hypersensitivity in BTBR model mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  415. Xiang Z et al. (1997). [The expression of IGF-1 and its receptor in cultured tendon cell] [PMID: 9868010]

    Laboratory literature summary: [The expression of IGF-1 and its receptor in cultured tendon cell]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  416. Williams DW et al. (1989). Evidence for autocrine production of IGF-1 in research subjects thyroid adenomas [PMID: 2744215]

    Laboratory literature summary: Evidence for autocrine production of IGF-1 in research subjects thyroid adenomas. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  417. Araki W et al. (2009). IGF-1 promotes beta-amyloid production by a secretase-independent mechanism [PMID: 19167357]

    Laboratory literature summary: IGF-1 promotes beta-amyloid production by a secretase-independent mechanism. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  418. Drakenberg K et al. (1993). Identification of IGF-1 receptors in primitive vertebrates [PMID: 8426910]

    Laboratory literature summary: Identification of IGF-1 receptors in primitive vertebrates. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  419. Kang BP et al. (2003). IGF-1 inhibits the mitochondrial apoptosis program in mesangial cells exposed to high… [PMID: 12876069]

    Laboratory literature summary: IGF-1 inhibits the mitochondrial apoptosis program in mesangial cells exposed to high glucose. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  420. Tomas-Martin P et al. (2015). Phospho-STIM1 is a downstream effector that mediates the signaling triggered by IGF-1… [PMID: 25562429]

    Laboratory literature summary: Phospho-STIM1 is a downstream effector that mediates the signaling triggered by IGF-1 in HEK293 cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  421. Pan YX et al. (2000). IGF-1 Antisense Strategies for oncology research models investigation [PMID: 21390807]

    Laboratory literature summary: IGF-1 Antisense Strategies for oncology research models investigation. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  422. Sriraman V et al. (2000). Effect of deprival of LH on Leydig cell proliferation: involvement of PCNA, cyclin D3… [PMID: 10854704]

    Laboratory literature summary: Effect of deprival of LH on Leydig cell proliferation: involvement of PCNA, cyclin D3 and IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  423. McMichael BK et al. (2017). The RhoGAP Myo9b Promotes Bone Growth by Mediating Osteoblastic Responsiveness to IGF-1 [PMID: 28585695]

    Laboratory literature summary: The RhoGAP Myo9b Promotes Bone Growth by Mediating Osteoblastic Responsiveness to IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  424. Rauch C et al. (2005). C2C12 skeletal muscle cells exposure to phosphatidylcholine triggers IGF-1 like-responses [PMID: 15956784]

    Laboratory literature summary: C2C12 skeletal muscle cells exposure to phosphatidylcholine triggers IGF-1 like-responses. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  425. Polgreen KE et al. (1994). Modulation of Pi transport in skeletal muscle by insulin and IGF-1 [PMID: 8086500]

    Laboratory literature summary: Modulation of Pi transport in skeletal muscle by insulin and IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  426. Chen WY et al. (2016). Self-Assembled Heterojunction Carbon Nanotubes Synergizing with Photoimmobilized IGF-1… [PMID: 27385628]

    Laboratory literature summary: Self-Assembled Heterojunction Carbon Nanotubes Synergizing with Photoimmobilized IGF-1 Inhibit Cellular Senescence. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  427. Su JL et al. (1997). Neutralizing IGF-1 monoclonal antibody with cross-species reactivity [PMID: 9455703]

    Laboratory literature summary: Neutralizing IGF-1 monoclonal antibody with cross-species reactivity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  428. Ding H et al. (1997). IGF-1 resistance in chronic renal failure: current evidence and possible mechanisms [PMID: 9350679]

    Laboratory literature summary: IGF-1 resistance in chronic renal failure: current evidence and possible mechanisms. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  429. Triebel J (2012). Laboratory research record on IGF-1 LR3 [PMID: 22339364]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  430. Hashimoto N et al. (2001). IGF-1 stimulates mucosal growth in ileal Thiry-Vella fistulas [PMID: 11379320]

    Laboratory literature summary: IGF-1 stimulates mucosal growth in ileal Thiry-Vella fistulas. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  431. Kuroda Y et al. (2015). Suppressive effect of membrane-permeable peptides derived from autophosphorylation… [PMID: 26276395]

    Laboratory literature summary: Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast oncology…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  432. Reiss K et al. (1995). Fibroblast proliferation during myocardial development in rats is regulated by IGF-1… [PMID: 7573538]

    Laboratory literature summary: Fibroblast proliferation during myocardial development in rats is regulated by IGF-1 receptors. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  433. Tamai J et al. (2025). Laboratory research record on IGF-1 LR3 [PMID: 40725173]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  434. Mockridge JW et al. (2000). IGF-1 regulates cardiac fibroblast apoptosis induced by osmotic stress [PMID: 10873605]

    Laboratory literature summary: IGF-1 regulates cardiac fibroblast apoptosis induced by osmotic stress. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  435. Decock A et al. (2021). In research subjects with controlled acromegaly, indices of glucose homeostasis… [PMID: 33715210]

    Laboratory literature summary: In research subjects with controlled acromegaly, indices of glucose homeostasis correlate with IGF-1 levels rather than with type of…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  436. Isgaard J et al. (1986). Effects of local administration of GH and IGF-1 on longitudinal bone growth in rats [PMID: 3963179]

    Laboratory literature summary: Effects of local administration of GH and IGF-1 on longitudinal bone growth in rats. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  437. Shavlakadze T et al. (2010). A growth stimulus is needed for IGF-1 to induce skeletal muscle hypertrophy in vivo [PMID: 20179101]

    Laboratory literature summary: A growth stimulus is needed for IGF-1 to induce skeletal muscle hypertrophy in vivo. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  438. Glick NR et al. (2001). The influence of nutrition on IGF-1 in tube-fed profoundly retarded adults [PMID: 11293472]

    Laboratory literature summary: The influence of nutrition on IGF-1 in tube-fed profoundly retarded adults. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  439. Decourtye L et al. (2017). IGF-1 Induces GHRH Neuronal Axon Elongation during Early Postnatal Life in Mice [PMID: 28076448]

    Laboratory literature summary: IGF-1 Induces GHRH Neuronal Axon Elongation during Early Postnatal Life in Mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  440. Joung YH et al. (2007). Hypoxia activates the IGF-1 expression through STAT5b in research subjects HepG2 cells [PMID: 17509524]

    Laboratory literature summary: Hypoxia activates the IGF-1 expression through STAT5b in research subjects HepG2 cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  441. Courtland HW et al. (2011). Growth hormone mediates pubertal skeletal development independent of hepatic IGF-1… [PMID: 20928887]

    Laboratory literature summary: Growth hormone mediates pubertal skeletal development independent of hepatic IGF-1 production. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  442. Brooker GJ et al. (2000). Endogenous IGF-1 regulates the neuronal differentiation of adult stem cells [PMID: 10679768]

    Laboratory literature summary: Endogenous IGF-1 regulates the neuronal differentiation of adult stem cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  443. Ito D et al. (2015). Biological activation of zirconia surfaces by chemical modification with IGF-1 [PMID: 25845378]

    Laboratory literature summary: Biological activation of zirconia surfaces by chemical modification with IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  444. Ito T et al. (2002). [IGF-1, IGFBP-3, PICP, ICTP] [PMID: 12599563]

    Laboratory literature summary: [IGF-1, IGFBP-3, PICP, ICTP]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  445. Lanz TA et al. (2008). Peripheral elevation of IGF-1 fails to alter Abeta clearance in multiple in vivo models [PMID: 18076866]

    Laboratory literature summary: Peripheral elevation of IGF-1 fails to alter Abeta clearance in multiple in vivo models. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  446. Dluzniewska J et al. (2005). A strong neuroprotective effect of the autonomous C-terminal peptide of IGF-1 Ec (MGF)… [PMID: 16144956]

    Laboratory literature summary: A strong neuroprotective effect of the autonomous C-terminal peptide of IGF-1 Ec (MGF) in brain ischemia. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  447. Walker KS et al. (2004). Resistance training alters plasma myostatin but not IGF-1 in healthy research subjects [PMID: 15126711]

    Laboratory literature summary: Resistance training alters plasma myostatin but not IGF-1 in healthy research subjects. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  448. Suttie JM et al. (1988). Elevated plasma IGF 1 levels in stags prevented from growing antlers [PMID: 3371270]

    Laboratory literature summary: Elevated plasma IGF 1 levels in stags prevented from growing antlers. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  449. Burchardt P et al. (2006). [IGF-1–a new risk factor for coronary atherosclerosis] [PMID: 17165168]

    Laboratory literature summary: [IGF-1–a new risk factor for coronary atherosclerosis]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  450. Kobayashi S et al. (2004). Age-related changes in IGF-1 expression in submandibular glands of… [PMID: 15287546]

    Laboratory literature summary: Age-related changes in IGF-1 expression in submandibular glands of senescence-accelerated mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  451. Irwin DM (2018). Viral Insulin/IGF-1-Like Peptides: Novel Regulators of Physiology and Pathophysiology? [PMID: 30304404]

    Laboratory literature summary: Viral Insulin/IGF-1-Like Peptides: Novel Regulators of Physiology and Pathophysiology?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  452. Liu Y et al. (2011). [Controlled release of fuctional proteins IGF-1, aFGF and VEGF through self-assembling… [PMID: 21604492]

    Laboratory literature summary: [Controlled release of fuctional proteins IGF-1, aFGF and VEGF through self-assembling peptide nanofiber hydrogel]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  453. D'Assante R et al. (2019). Research subjects heart shifts from IGF-1 production to utilization with chronic heart… [PMID: 31267324]

    Laboratory literature summary: research subjects heart shifts from IGF-1 production to utilization with chronic heart failure. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  454. Guan L et al. (2012). [Effects of gibberellins on early development and IGF-1 expression in research models… [PMID: 23050434]

    Laboratory literature summary: [Effects of gibberellins on early development and IGF-1 expression in research models rats]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  455. Escartin C et al. (2007). IGF-1 exacerbates the neurotoxicity of the mitochondrial inhibitor 3NP in rats [PMID: 17868993]

    Laboratory literature summary: IGF-1 exacerbates the neurotoxicity of the mitochondrial inhibitor 3NP in rats. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  456. Desautels M et al. (1996). Comparison of trophic effects of norepinephrine, insulin, and IGF-1 in mouse brown… [PMID: 8764296]

    Laboratory literature summary: Comparison of trophic effects of norepinephrine, insulin, and IGF-1 in mouse brown adipocytes. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  457. Saggese R et al. (2005). The IGF-1–IGFBPs system in the crevicular fluid: its changes during orthodontic movement [PMID: 15977342]

    Laboratory literature summary: The IGF-1–IGFBPs system in the crevicular fluid: its changes during orthodontic movement. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  458. Gu Y et al. (2004). Effect of IGF-1 on the balance between autophagy of dysfunctional mitochondria and… [PMID: 15556609]

    Laboratory literature summary: Effect of IGF-1 on the balance between autophagy of dysfunctional mitochondria and apoptosis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  459. Allison M (2012). Laboratory setbacks reduce IGF-1 inhibitors to cocktail mixers [PMID: 23051797]

    Laboratory literature summary: laboratory setbacks reduce IGF-1 inhibitors to cocktail mixers. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  460. Payne AM et al. (2006). Motor neurone targeting of IGF-1 prevents specific force decline in ageing mouse muscle [PMID: 16293644]

    Laboratory literature summary: Motor neurone targeting of IGF-1 prevents specific force decline in ageing mouse muscle. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  461. McColl KE (2012). Serum IGF-1 linking visceral metabolic research models with esophageal adenocarcinoma:… [PMID: 22306944]

    Laboratory literature summary: Serum IGF-1 linking visceral metabolic research models with esophageal adenocarcinoma: unconvincing evidence. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  462. Baserga R (1992). IGF-1 receptor as the restriction point of the cell cycle [PMID: 1482048]

    Laboratory literature summary: IGF-1 receptor as the restriction point of the cell cycle. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  463. Bassett NS et al. (1990). Plasma clearance of radiolabelled IGF-1 in the late gestation ovine fetus [PMID: 1965440]

    Laboratory literature summary: Plasma clearance of radiolabelled IGF-1 in the late gestation ovine fetus. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  464. Osorio FG et al. (2016). Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating… [PMID: 26692333]

    Laboratory literature summary: Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  465. Bartolomucci A et al. (2007). Chronic intracerebroventricular TLQP-21 delivery does not modulate the GH/IGF-1-axis… [PMID: 17400498]

    Laboratory literature summary: Chronic intracerebroventricular TLQP-21 delivery does not modulate the GH/IGF-1-axis and muscle strength in mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  466. Yamada N et al. (2006). Laboratory research record on IGF-1 LR3 [PMID: 16877393]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  467. Kitamei H et al. (2005). Retinal neovascularization during investigation with IGF-1 for insulin resistance syndrome [PMID: 15672252]

    Laboratory literature summary: Retinal neovascularization during investigation with IGF-1 for insulin resistance syndrome. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  468. Yoshitake S et al. (1996). [IGF-1 levels in elderly research subjects during perioperative period] [PMID: 8953865]

    Laboratory literature summary: [IGF-1 levels in elderly research subjects during perioperative period]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  469. Goodman-Gruen D et al. (2000). IGF-1 and ischemic heart disease in older people [PMID: 10894338]

    Laboratory literature summary: IGF-1 and ischemic heart disease in older people. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  470. Lansang C et al. (2005). Serum IGF-1 in studied acromegaly – how normal is "normal"? [PMID: 16379035]

    Laboratory literature summary: Serum IGF-1 in studied acromegaly – how normal is "normal"?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  471. Chen XD et al. (2000). [Effect of electroacupuncture on mRNA expression of NGF and IGF-1 in injured nerve] [PMID: 12516429]

    Laboratory literature summary: [Effect of electroacupuncture on mRNA expression of NGF and IGF-1 in injured nerve]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  472. Brower V (1998). Prostate-oncology research models link sours IGF-1 [PMID: 9583942]

    Laboratory literature summary: Prostate-oncology research models link sours IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  473. Pereira EA et al. (2010). Reduction of elevated IGF-1 levels in coincident amyotrophic lateral sclerosis and… [PMID: 19634028]

    Laboratory literature summary: Reduction of elevated IGF-1 levels in coincident amyotrophic lateral sclerosis and acromegaly. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  474. Coxam V et al. (1992). The influence of parathyroid hormone-related protein on hepatic IGF-1 production [PMID: 1306983]

    Laboratory literature summary: The influence of parathyroid hormone-related protein on hepatic IGF-1 production. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  475. Eiam-ong S et al. (1996). Renal ATPases twenty-four hours after uninephrectomy: the role of IGF-1 [PMID: 8807627]

    Laboratory literature summary: Renal ATPases twenty-four hours after uninephrectomy: the role of IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  476. Gutiérrez S et al. (2005). Antagonic effects of oestradiol in interaction with IGF-1 on proliferation of… [PMID: 16133120]

    Laboratory literature summary: Antagonic effects of oestradiol in interaction with IGF-1 on proliferation of lactotroph cells in vitro. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  477. Jian-bo L et al. (2010). Laboratory research record on IGF-1 LR3 [PMID: 20406575]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  478. Faidley TD et al. (2006). Inhibition of dipeptidyl-peptidase IV does not increase circulating IGF-1… [PMID: 16946406]

    Laboratory literature summary: Inhibition of dipeptidyl-peptidase IV does not increase circulating IGF-1 concentrations in growing pigs. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  479. Lee W et al. (2014). Directed axonal outgrowth using a propagating gradient of IGF-1 [PMID: 24664530]

    Laboratory literature summary: Directed axonal outgrowth using a propagating gradient of IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  480. Akin F et al. (2008). GH/IGF-1 axis in research subjects with subclinical hypothyroidism [PMID: 18031318]

    Laboratory literature summary: GH/IGF-1 axis in research subjects with subclinical hypothyroidism. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  481. Chevalier RL et al. (2000). Renal tubulointerstitial injury from ureteral obstruction in the neonatal rat is… [PMID: 10720941]

    Laboratory literature summary: Renal tubulointerstitial injury from ureteral obstruction in the neonatal rat is attenuated by IGF-1. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  482. Shang J et al. (2006). [Effect of overload environment on IGF-1 expression of osteoblasts] [PMID: 17228745]

    Laboratory literature summary: [Effect of overload environment on IGF-1 expression of osteoblasts]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  483. Xian CY et al. (2005). [IGF-1 alternative splice isoforms: mechano growth factor] [PMID: 16408771]

    Laboratory literature summary: [IGF-1 alternative splice isoforms: mechano growth factor]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  484. Howe CL et al. (2009). Laboratory research record on IGF-1 LR3 [PMID: 19822878]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  485. Lee JT et al. (2008). Unraveling the mysteries of IGF-1 signaling in melanoma [PMID: 18478012]

    Laboratory literature summary: Unraveling the mysteries of IGF-1 signaling in melanoma. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  486. Shepherd PR (2004). Secrets of insulin and IGF-1 regulation of insulin secretion revealed [PMID: 14672535]

    Laboratory literature summary: Secrets of insulin and IGF-1 regulation of insulin secretion revealed. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  487. Deshayes K et al. (2002). Rapid identification of small binding motifs with high-throughput phage display:… [PMID: 11983338]

    Laboratory literature summary: Rapid identification of small binding motifs with high-throughput phage display: discovery of peptidic antagonists of IGF-1 function. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  488. Ernst S et al. (2013). A quantitative approach for assessing significant improvements in elite sprint… [PMID: 22930482]

    Laboratory literature summary: A quantitative approach for assessing significant improvements in elite sprint performance: has IGF-1 entered the arena?. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  489. Sharma S et al. (2008). Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with… [PMID: 18775495]

    Laboratory literature summary: Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signaling. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  490. Ish-Shalom D et al. (1995). Mitogenic potential of insulin on lymphoma cells lacking IGF-1 receptor [PMID: 7486686]

    Laboratory literature summary: Mitogenic potential of insulin on lymphoma cells lacking IGF-1 receptor. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  491. Rauch C et al. (2005). Inward relocation of exogenous phosphatidylserine triggered by IGF-1 in non-apoptotic… [PMID: 16184625]

    Laboratory literature summary: Inward relocation of exogenous phosphatidylserine triggered by IGF-1 in non-apoptotic C2C12 cells is concentration dependent. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  492. Komamura K (2007). [Growth factor research protocol for heart failure: IGF-1] [PMID: 17571382]

    Laboratory literature summary: [Growth factor research protocol for heart failure: IGF-1]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  493. Osborne R (2008). Commercial interest waxes for IGF-1 blockers [PMID: 18612276]

    Laboratory literature summary: Commercial interest waxes for IGF-1 blockers. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  494. Liu JK et al. (2009). The modulation of IGF-1 signalling by the intestine-specific factor CDX2 [PMID: 19671549]

    Laboratory literature summary: The modulation of IGF-1 signalling by the intestine-specific factor CDX2. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  495. Valtorta A et al. (1990). [In vitro effects of GH and IGF-1 on natural cytostatic activity] [PMID: 2273948]

    Laboratory literature summary: [In vitro effects of GH and IGF-1 on natural cytostatic activity]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  496. Mitchell P (1997). Laboratory research record on IGF-1 LR3 [PMID: 9424556]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  497. Hayakawa Y et al. (2004). Structure of tyroscherin, an antitumor antibiotic against IGF-1-dependent cells from… [PMID: 15638323]

    Laboratory literature summary: Structure of tyroscherin, an antitumor antibiotic against IGF-1-dependent cells from Pseudallescheria sp. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  498. Guidi A et al. (2007). An immunoenzymatic method to measure IGF-1 in milk [PMID: 17682917]

    Laboratory literature summary: An immunoenzymatic method to measure IGF-1 in milk. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  499. Garber K (2005). IGF-1: old growth factor shines as new drug target [PMID: 15928295]

    Laboratory literature summary: IGF-1: old growth factor shines as new drug target. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  500. Suzuki N et al. (2007). Involvement of IGF-1/LARG signaling in the differentiation of neural stem cells into… [PMID: 17384471]

    Laboratory literature summary: Involvement of IGF-1/LARG signaling in the differentiation of neural stem cells into oligodendrocytes. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  501. Luo J et al. (2024). Restoring brain health: Electroacupuncture at GB20 and LR3 for migraine mitigation… [PMID: 39036293]

    Laboratory literature summary: Restoring brain health: Electroacupuncture at GB20 and LR3 for migraine mitigation through mitochondrial restoration. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  502. Chen D et al. (1999). Molecular cloning of mouse Lrp7(Lr3) cDNA and chromosomal mapping of orthologous genes… [PMID: 10049586]

    Laboratory literature summary: Molecular cloning of mouse Lrp7(Lr3) cDNA and chromosomal mapping of orthologous genes in mouse and research subjects. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  503. White A et al. (2023). Laboratory research record on IGF-1 LR3 [PMID: 37114757]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  504. Dong Y et al. (1998). Molecular cloning and characterization of LR3, a novel LDL receptor family protein… [PMID: 9790987]

    Laboratory literature summary: Molecular cloning and characterization of LR3, a novel LDL receptor family protein with mitogenic activity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  505. White A et al. (2025). Laboratory research record on IGF-1 LR3 [PMID: 39679943]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

  506. Zhang Q et al. (2021). [Electroacupuncture at "Taichong"(LR3) improves baroreflex sensitivity and… [PMID: 33798290]

    Laboratory literature summary: [Electroacupuncture at "Taichong"(LR3) improves baroreflex sensitivity and α2-adrenergic receptor activity in nucleus tractus solitarii…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  507. Yavuz E et al. (2025). Revolutionary decellularized Alstroemeria stem-based nerve conduit integrated with… [PMID: 41015370]

    Laboratory literature summary: Revolutionary decellularized Alstroemeria stem-based nerve conduit integrated with GelMA and controlled IGF-1 LR3 release for enhanced…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  508. Wangsa-Wirawan ND et al. (2001). Physicochemical characteristics of LR3-IGF1 protein inclusion bodies: electrophoretic… [PMID: 11485445]

    Laboratory literature summary: Physicochemical characteristics of LR3-IGF1 protein inclusion bodies: electrophoretic mobility studies. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  509. Cheng Z et al. (2025). Laboratory research record on IGF-1 LR3 [PMID: 40670170]

    PubMed laboratory record discussing IGF-1 LR3 in a research context. Review the full methods and limitations on PubMed; research use only.

Browse the full PubMed index: PubMed search.

Additional information

Weight .125 lbs
Dimensions 9 × 7 × .5 in
Size: No selection

0.1mg, 1mg

Keep lyophilized peptides sealed in their original vial, protected from light and humidity, and store at -4°F or colder for optimal long-term stability in research settings; short-term refrigeration at around 39°F suffices for immediate use within weeks, though freezer storage maximizes integrity across extended research timelines.

Frequently Asked Questions

What is IGF-1 LR3 peptide?

IGF-1 LR3 is a synthetic analog of insulin-like growth factor-1 (IGF-1). It is studied in research laboratories for its role in cellular signaling, receptor interactions, and growth factor-related pathways.

What is IGF-1 LR3 used for in research?

IGF-1 LR3 is used in research laboratories to investigate growth factor signaling, peptide-receptor interactions, and cellular pathway activity. It is not approved for human use.

Is IGF-1 LR3 Peptide approved or intended for human use?

No. IGF-1 LR3 is strictly intended for research purposes only and is not approved by the FDA for human use.

Is IGF-1 LR3 Peptide FDA-approved for medical or clinical use?

No. IGF-1 LR3 is not approved by the U.S. Food and Drug Administration for any medical, therapeutic, or diagnostic use.

In what form is IGF-1 LR3 supplied?

IGF-1 LR3 is supplied as a lyophilized (freeze-dried) peptide powder for use in controlled research laboratories.

How should IGF-1 LR3 be stored?

Store sealed, lyophilized peptides protected from light and humidity at -4°F or colder; refrigeration (~39°F) is suitable for short-term use.

What vial sizes are available for IGF-1 LR3?

IGF-1 LR3 is available in multiple vial sizes.

Is IGF-1 LR3 Peptide sold as a prescription product?

No prescription is required; however, it is sold strictly for research use only.

How is IGF-1 LR3 shipped?

Orders are processed and shipped using secure, protective packaging to maintain product integrity during transit. For more info, visit: https://www.nationwidepeptides.com/shipping-and-payments

How can I verify IGF-1 LR3 purity and quality?

Product quality is supported through third-party laboratory testing and Certificates of Analysis (COA), confirming purity and batch consistency. For more info, visit: https://www.nationwidepeptides.com/coa/