DSIP (Delta Sleep-Inducing Peptide) was first isolated from cerebral venous blood of rabbits in 1977. It is an amphiphilic nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) that has been extensively studied for its role in modulation of the sleep-wake cycle, hypothalamic-pituitary-adrenal (HPA) axis activity, and various neuroendocrine functions. Research indicates that DSIP promotes slow-wave (delta) sleep and interacts with stress-related hormonal pathways in animal models. It has also been studied for potential analgesic, anticonvulsant, and antioxidant effects. The product is provided as a lyophilized powder with high purity (≥98% by HPLC/MS) and includes full analytical documentation for research use only. DSIP is manufactured under GMP-aligned, ISO-compliant conditions to ensure quality and consistency. It is strictly for research applications and not intended for human use or therapeutic purposes.
DSIP (Delta Sleep-Inducing Peptide)
Price range: $54.00 through $66.00
DSIP (Delta Sleep-Inducing Peptide) is a synthetic research-grade neuropeptide studied for its effects on sleep regulation and stress response.
Additional information
| Weight | .125 lbs |
|---|---|
| Dimensions | 9 × 7 × .5 in |
| Size: No selection | 5mg, 10mg, 15mg |
Peptide Research
- Schoenenberger GA (1983) DSIP: a review [PMID: 6313035, https://pubmed.ncbi.nlm.nih.gov/6313035/].
- Wang Y et al. (2024) DSIP-CBBBP in insomnia mice [DOI: 10.3389/fphar.2024.1439536, https://www.frontiersin.org/articles/10.3389/fphar.2024.1439536/full].
- Graf MV et al. (1984) DSIP in chronic insomniacs [PMID: 6391926, https://pubmed.ncbi.nlm.nih.gov/6391926/].
- Larbig W et al. (1984) DSIP in chronic pain [PMID: 6548970, https://pubmed.ncbi.nlm.nih.gov/6548970/].
- Iyer KS et al. (1988) DSIP and GH release [PMID: 3333072, https://pubmed.ncbi.nlm.nih.gov/3333072/
- Schneider-Helmert D et al. (1981) Acute effects on human sleep [PMID: 6895513, https://pubmed.ncbi.nlm.nih.gov/6895513/].
- Alzheimer’s Drug Discovery Foundation (2025) DSIP cognitive vitality [https://www.alzdiscovery.org/uploads/cognitive_vitality_media/Semax-Cognitive-Vitality-For-Researchers.pdf].
- Khvatova EM et al. (2003) DSIP stress protection [DOI: 10.1016/S0196-9781(03)00040-8, https://www.sciencedirect.com/science/article/abs/pii/S0196978103000408].
- Innerbody (2025) DSIP benefits/risks
https://www.innerbody.com/dsip-delta-sleep-inducing-peptide
Keep lyophilized peptides sealed in their original vial, protected from light and humidity, and store at -4°F or colder for optimal long-term stability in research settings; short-term refrigeration at around 39°F suffices for immediate use within weeks, though freezer storage maximizes integrity across extended research timelines.






