Adipotide (also known as FTPP or Prohibitin-TP01) is a peptidomimetic research compound comprising two functional domains:
- CKGGRAKDC – a homing motif theorized to selectively bind prohibitin and annexin A2 (ANXA2) on the surface of white adipose tissue blood-vessel endothelium.
- D(KLAKLAK)₂ – a cationic, amphipathic proapoptotic sequence hypothesized to disrupt mitochondrial membranes (clinicalgate.com)
According to published preclinical literature, Adipotide is theorized to trigger apoptosis of white adipose vasculature following internalization. Research on obese primate models has been published in peer-reviewed journals (pmc.ncbi.nlm.nih.gov). This research-grade lyophilized peptide is synthesized under strict quality controls and is accompanied by full analytical documentation, making it a tool for adipose vasculature biology and related in vitro research.
For Research Use Only. Not for human use.
Key Scientific Attributes
- High-purity Adipotide (≥98% by HPLC/MS, TFA salt form)
- Verified dual-domain sequence: CKGGRAKDC-GG-D(KLAKLAK)₂ (cyclic via disulfide)
- Lyophilized formulation for long-term stability
- Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
- Manufactured in GMP-aligned, ISO-compliant facilities
- Intended for in vitro and preclinical research into prohibitin targeting and adipose vasculature apoptosis
Research-Referenced Attributes (Based on scientific literature only; not intended as therapeutic claims. All findings are from preclinical models.)
- Hypothesized selective apoptosis of white-fat endothelium in preclinical research models (rightpatient.com)
- Preclinical studies report observed changes in adipose tissue volume and metabolic parameters in obese animal models
- Theorized to have no effect on lean tissue vasculature in research models
- Research tool relevant to adipose biology, metabolic syndrome models, and angiogenesis studies
Why Researchers Choose This Adipotide
- Sequence consistent with that used in published MD Anderson / Arrowhead research studies
- Transparent analytical data (HPLC >98%, MS confirmation of both domains)
- Suitable for obesity biology, vascular biology, and oncology laboratory research
- Competitive research pricing with bulk options
For Research Use Only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.
