PE-22-28 is a synthetic analog derived from the endogenous sortilin propeptide, spadin, used in preclinical research to selectively block the TREK-1 potassium channel. It regulates neuronal excitability, synaptic plasticity, and mood-related behaviors in laboratory models. The peptide is produced under GMP-compliant conditions and supplied as a lyophilized powder with full quality documentation including a Certificate of Analysis. It acts as a potent antagonist of TREK-1, enhancing neuronal depolarization and serotonergic neuron activity. Research indicates its role in modulating TREK-1 activity, promoting hippocampal neurogenesis and synaptogenesis, and influencing stress and mood regulation in preclinical studies. It is intended for research use only and not for human use.
PE-22-28 Peptide
PE-22-28 Peptide
Price range: $52.00 through $63.00
PE-22-28 is a research-grade synthetic peptide that selectively blocks TREK-1 potassium channels for preclinical studies on neuronal and mood regulation.
Additional information
| Weight | .125 lbs |
|---|---|
| Dimensions | 9 × 7 × .5 in |
| Size: No selection | 5mg, 10mg |
Keep lyophilized peptides sealed in their original vial, protected from light and humidity, and store at -4°F or colder for optimal long-term stability in research settings; short-term refrigeration at around 39°F suffices for immediate use within weeks, though freezer storage maximizes integrity across extended research timelines.
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