GDF-8 Peptide

$99.00

Laboratory-grade GDF-8 Peptide is myostatin (GDF-8), a TGF-beta family ligand used in muscle-biology research. Research buyers select this listing for pre-clinical work on myostatin/ActRII pathway assays—not for clinical, veterinary, or consumer use.

For Research Use Only. Not for human use.

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For Research Use Only — Not for Human Consumption
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For Research Use Only. Not for human use.

GDF-8 Peptide research-grade

Overview

Laboratory-grade GDF-8 Peptide presents as a myostatin (GDF-8), a TGF-beta family ligand used in muscle-biology research. Nationwide lists this SKU for controlled research programs focused on myostatin/ActRII pathway assays—not for clinical, veterinary, or consumer use.

Research buyers specify GDF-8 Peptide when protocols require a characterized input for myostatin/ActRII pathway assays. Typical deployments include cell-based or cell-free assays, method development plates, and pathway-mapping models executed under institutional laboratory SOPs.

The catalog record supports pre-clinical documentation trails across replicates and partner sites. Archive shipment paperwork with study files whenever GDF-8 Peptide enters a new experimental series.

Research Context for GDF-8 Peptide

Work involving GDF-8 Peptide typically focuses on in vitro systems, assay development, and mechanistic model studies.

Teams confirm lot details before setup so conditions stay traceable across repeats and collaborative sites.

Published literature can inform starting ranges for related experimental designs. Each laboratory should still validate performance with its own instruments, plates, and detection chemistry.

Pilot runs are useful before committing larger plate sets, especially when detection chemistry or incubation windows are being optimized.

Documented Attributes

Key catalog attributes for this material include:

  • Research-grade material intended for laboratory investigation only
  • Catalog labeling aligned with research procurement channels
  • Suitable for method development and comparative assay workflows
  • Documentation packages available where provided for the listed lot

Laboratory Handling Notes

Receiving and Identity Checks

Before opening a vial of GDF-8 Peptide, confirm the physical label against the purchase order and packing list.

Retain outer packaging until identity checks are complete, and report damaged seals to purchasing before experimental work continues.

Reconstitution and Aliquoting

Handle this material according to institutional SOPs for weighing, reconstitution, aliquoting, and storage.

Record lot identifiers in laboratory notebooks before reconstitution. Verify solvent compatibility and storage temperature against your validated process.

Prepare assay buffers and consumables before opening the vial to reduce hold time. Keep unused aliquots labeled with date, solvent, and concentration for later repeats.

Chain of Custody

Keep chain-of-custody notes with inventory checks when material moves between freezers or benches.

Use dedicated spatulas and clean balances to avoid cross-contamination between catalog items. Schedule thaw cycles intentionally rather than repeated freeze-thaw of the same aliquot.

Secondary containment trays reduce spill risk during multi-step reconstitution. Cold-chain interruptions should be noted even when the vial remains sealed.

Why Laboratories Source GDF-8 Peptide

Procurement and research teams often select this catalog item because it supports:

  • Clear research-use labeling for compliance-aligned purchasing
  • Consistent product identification across multi-lot studies
  • Fit for reference, screening, and mechanistic laboratory models
  • Straightforward catalog support for planning and documentation

Study Planning and Quality Documentation

Before starting experimental work with GDF-8 Peptide, review any COA or quality files provided with the shipment.

Align your protocol with institutional research requirements and keep use within the labeled research context.

File catalog documentation with the study records at receipt. These steps help keep experiments comparable over time when using GDF-8 Peptide in sequential study phases.

Method Development Tips

Method development often begins with small pilot plates before larger screening panels.

Document buffer lots, incubation times, and detection settings alongside the material lot number.

If results diverge from historical baselines, re-check reconstitution volume and storage history first. Shared equipment logs help explain variance when multiple operators run the same protocol.

Inventory and Training

Update digital inventory immediately after opening a new lot of GDF-8 Peptide.

Training new staff on labeling conventions reduces mix-ups across similar catalog SKUs. When transferring methods between sites, share both the written SOP and the lot metadata package.

Dispose of residual solutions according to institutional chemical hygiene rules. Do not repurpose research materials for any non-laboratory application.

Periodic inventory reconciliation keeps expired or depleted lots from entering active workflows. For related catalog options, browse adjacent research categories on this site after confirming your assay needs.

For Research Use Only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease.

Peptide Research

For Research Use Only. Not for human use.

PubMed (NIH/NLM) records related to this compound for laboratory literature review. Inclusion does not imply suitability for any use beyond controlled research. Each note below is a research-framed summary using compliance-safe wording.

Showing 31 PubMed records. Displaying 10 per page.

  1. Zheng X et al. (2022). Regulatory Role and Potential Importance of GDF-8 in Ovarian Reproductive Activity [PMID: 35692411]

    Laboratory literature summary: Regulatory Role and Potential Importance of GDF-8 in Ovarian Reproductive Activity. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  2. Elkasrawy MN et al. (2010). Myostatin (GDF-8) as a key factor linking muscle mass and bone structure [PMID: 20190380]

    Laboratory literature summary: Myostatin (GDF-8) as a key factor linking muscle mass and bone structure. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  3. Chen J et al. (2023). Snail mediates GDF-8-stimulated research subjects extravillous trophoblast cell… [PMID: 37143106]

    Laboratory literature summary: Snail mediates GDF-8-stimulated research subjects extravillous trophoblast cell invasion by upregulating MMP2 expression. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  4. Fang L et al. (2021). GDF-8 stimulates trophoblast cell invasion by inducing ALK5-SMAD2/3-mediated MMP2… [PMID: 34432647]

    Laboratory literature summary: GDF-8 stimulates trophoblast cell invasion by inducing ALK5-SMAD2/3-mediated MMP2 expression. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  5. Palandra J et al. (2016). Quantitative measurements of GDF-8 using immunoaffinity LC-MS/MS [PMID: 26846723]

    Laboratory literature summary: Quantitative measurements of GDF-8 using immunoaffinity LC-MS/MS. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  6. Wallner C et al. (2020). Regulatory aspects of myogenic factors GDF-8 and Follistatin on the intake of combined… [PMID: 31526145]

    Laboratory literature summary: Regulatory aspects of myogenic factors GDF-8 and Follistatin on the intake of combined oral contraceptives. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  7. Jiang MS et al. (2004). Characterization and identification of the inhibitory domain of GDF-8 propeptide [PMID: 14975732]

    Laboratory literature summary: Characterization and identification of the inhibitory domain of GDF-8 propeptide. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  8. Ochsner UA et al. (2019). Targeting Unique Epitopes on Highly Similar Proteins GDF-11 and GDF-8 with Modified… [PMID: 31638376]

    Laboratory literature summary: Targeting Unique Epitopes on Highly Similar Proteins GDF-11 and GDF-8 with Modified DNA Aptamers. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  9. Philip B et al. (2005). Regulation of GDF-8 signaling by the p38 MAPK [PMID: 15567067]

    Laboratory literature summary: Regulation of GDF-8 signaling by the p38 MAPK. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  10. Wong CL et al. (2009). Growth-differentiation factor-8 (GDF-8) in the uterus: its identification and… [PMID: 19930721]

    Laboratory literature summary: Growth-differentiation factor-8 (GDF-8) in the uterus: its identification and functional significance in the golden hamster. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  11. Manickam R et al. (2008). Mammary gland differentiation inversely correlates with GDF-8 expression [PMID: 18389502]

    Laboratory literature summary: Mammary gland differentiation inversely correlates with GDF-8 expression. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  12. Thies RS et al. (2001). GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting… [PMID: 11519824]

    Laboratory literature summary: GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  13. Fang L et al. (2016). Serum GDF-8 levels change dynamically during controlled ovarian hyperstimulation in… [PMID: 27329327]

    Laboratory literature summary: Serum GDF-8 levels change dynamically during controlled ovarian hyperstimulation in research subjects undergoing assisted-reproduction…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  14. Fang L et al. (2021). High ovarian GDF-8 levels contribute to elevated estradiol production in ovarian… [PMID: 34239360]

    Laboratory literature summary: High ovarian GDF-8 levels contribute to elevated estradiol production in ovarian hyperstimulation syndrome by stimulating aromatase…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  15. Le W et al. (2017). The Effect of Myostatin (GDF-8) on Proliferation and Tenocyte Differentiation of Rat… [PMID: 28506172]

    Laboratory literature summary: The Effect of Myostatin (GDF-8) on Proliferation and Tenocyte Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  16. Jerobin J et al. (2021). Regulation of circulating CTRP-2/CTRP-9 and GDF-8/GDF-15 by intralipids and insulin in… [PMID: 33874963]

    Laboratory literature summary: Regulation of circulating CTRP-2/CTRP-9 and GDF-8/GDF-15 by intralipids and insulin in healthy control and polycystic ovary syndrome…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  17. Fulzele S et al. (2010). Role of myostatin (GDF-8) signaling in the research subjects anterior cruciate ligament [PMID: 20186835]

    Laboratory literature summary: Role of myostatin (GDF-8) signaling in the research subjects anterior cruciate ligament. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  18. Fang L et al. (2020). High GDF-8 in follicular fluid is associated with a low developmental research context… [PMID: 32272446]

    Laboratory literature summary: High GDF-8 in follicular fluid is associated with a low developmental research context rate in assisted-reproduction research models…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  19. Elkasrawy M et al. (2011). Myostatin (GDF-8) inhibits chondrogenesis and chondrocyte proliferation in vitro by… [PMID: 21756198]

    Laboratory literature summary: Myostatin (GDF-8) inhibits chondrogenesis and chondrocyte proliferation in vitro by suppressing Sox-9 expression. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  20. Kellum E et al. (2009). Myostatin (GDF-8) deficiency increases fracture callus size, Sox-5 expression, and… [PMID: 18852073]

    Laboratory literature summary: Myostatin (GDF-8) deficiency increases fracture callus size, Sox-5 expression, and callus bone volume. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  21. Vecchione L et al. (2010). Age-related changes in craniofacial morphology in GDF-8 (myostatin)-deficient mice [PMID: 19899116]

    Laboratory literature summary: Age-related changes in craniofacial morphology in GDF-8 (myostatin)-deficient mice. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  22. Yang Z et al. (2008). A retrovirus-based system to stably silence GDF-8 expression and enhance myogenic… [PMID: 18563849]

    Laboratory literature summary: A retrovirus-based system to stably silence GDF-8 expression and enhance myogenic differentiation in research subjects rhabdomyosarcoma…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  23. Kamanga-Sollo E et al. (2003). Role of insulin-like growth factor binding protein (IGFBP)-3 in TGF-beta- and GDF-8… [PMID: 14502562]

    Laboratory literature summary: Role of insulin-like growth factor binding protein (IGFBP)-3 in TGF-beta- and GDF-8 (myostatin)-induced suppression of proliferation in…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  24. Elkasrawy M et al. (2012). Laboratory research record on GDF-8 [PMID: 22205678]

    PubMed laboratory record discussing GDF-8 in a research context. Review the full methods and limitations on PubMed; research use only.

  25. Hamrick MW et al. (2010). Recombinant myostatin (GDF-8) propeptide enhances the repair and regeneration of both… [PMID: 20173658]

    Laboratory literature summary: Recombinant myostatin (GDF-8) propeptide enhances the repair and regeneration of both muscle and bone in a model of deep penetrant…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  26. Hamrick MW et al. (2003). Bone architecture and disc degeneration in the lumbar spine of mice lacking GDF-8… [PMID: 14554215]

    Laboratory literature summary: Bone architecture and disc degeneration in the lumbar spine of mice lacking GDF-8 (myostatin). Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  27. Liu C et al. (2008). [Inhibiting GDF-8 expression by retrovirus-based RNAi stably] [PMID: 18464609]

    Laboratory literature summary: [Inhibiting GDF-8 expression by retrovirus-based RNAi stably]. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  28. Seibert MJ et al. (2001). Polymorphic variation in the research subjects myostatin (GDF-8) gene and association… [PMID: 11555072]

    Laboratory literature summary: Polymorphic variation in the research subjects myostatin (GDF-8) gene and association with strength measures in the research subjects's…. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  29. Tantia MS et al. (2006). Comparative analysis of GDF 8 (myostatin) in Bos indicus and Bos taurus [PMID: 17312952]

    Laboratory literature summary: Comparative analysis of GDF 8 (myostatin) in Bos indicus and Bos taurus. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  30. Tantia MS et al. (2007). Sequence of GDF 8 (myostatin) gene in Bubalus bubalis [PMID: 17612840]

    Laboratory literature summary: Sequence of GDF 8 (myostatin) gene in Bubalus bubalis. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

  31. Wiener P et al. (2009). Assessment of selection mapping near the myostatin gene (GDF-8) in cattle [PMID: 19456316]

    Laboratory literature summary: Assessment of selection mapping near the myostatin gene (GDF-8) in cattle. Consult the PubMed record for methods, models, and limitations. Presented for research literature review only

Browse the full PubMed index: PubMed search.

Additional information

Weight .125 lbs
Dimensions 9 × 7 × .5 in

Keep lyophilized peptides sealed in their original vial, protected from light and humidity, and store at -4°F or colder for optimal long-term stability in research settings; short-term refrigeration at around 39°F suffices for immediate use within weeks, though freezer storage maximizes integrity across extended research timelines.

Frequently Asked Questions

What is GDF-8 Peptide?

GDF-8 Peptide is supplied as a research-grade catalog material for controlled laboratory investigation only.

What is GDF-8 Peptide used for?

This product is intended for research purposes only and is not approved for human or clinical use.

What form does GDF-8 Peptide come in?

Most catalog items in this range are supplied as lyophilized (freeze-dried) powder unless otherwise stated on the product page.

How should GDF-8 Peptide be stored?

Store according to the product label and your institutional SOPs, typically in a cool, dry place. Refrigeration or freezer storage may be required depending on the material.

Is this product safe for human use?

No. This product is strictly labeled for research use only and is not for human use.

Do I need a prescription to purchase this product?

Because it is sold as a research chemical, a prescription is not required. Use is restricted to laboratory research.

How is the product shipped?

Shipping methods and transit times vary. Products are packed for secure transit. For more info, visit: https://www.nationwidepeptides.com/shipping-and-payments/

Is there a return or refund policy?

Policies cover damaged or faulty shipments; returns are limited due to the nature of research materials. For more info, visit: https://www.nationwidepeptides.com/return-policy/

How do I verify product quality?

Quality documentation may include third-party testing or certificates of analysis (COA) where provided. For more info, visit: https://www.nationwidepeptides.com/coa/