Follistatin 344 is the predominant circulating isoform of follistatin, a naturally occurring glycoprotein that binds and neutralizes myostatin (GDF-8), activin A, and other TGF-β family members. First identified in ovarian follicular fluid as an activin antagonist, it is recognized as a potent endogenous inhibitor of myostatin, making it a subject of interest in skeletal muscle cell research. According to pmc.ncbi.nlm.nih.gov, follistatin has been investigated in the context of myostatin inhibition in preclinical research models. This research-grade lyophilized protein is produced under strict quality controls and provided with full analytical documentation. For Research Use Only. Not for human use.
Key Scientific Attributes
- High-purity Follistatin 344 (≥ 98% by HPLC/SDS-PAGE, recombinant human sequence)
- Verified 344-amino-acid mature isoform (Gly30–Asp344) with correct disulfide bonding
- Lyophilized formulation for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, SDS-PAGE, myostatin/activin binding ELISA, and endotoxin testing
- Manufactured in GMP-aligned, ISO-compliant facilities
- Suitable for myostatin blockade and TGF-β antagonism studies in laboratory settings
Research-Referenced Attributes (Based on scientific literature; not therapeutic claims.)
- Studies suggest Follistatin 344 may modulate satellite cell activity and myostatin signalling pathways in in vitro and preclinical research models, as noted by openmedscience.com
- Research indicates potential interactions with activin A signalling pathways relevant to cancer cachexia and reproductive biology research contexts
- Investigated in laboratory models relevant to neuromuscular biology and TGF-β superfamily signalling.
Why Researchers Choose This Follistatin 344
- Recombinant human sequence with documented myostatin-neutralizing activity in binding assays
- Transparent analytical data (HPLC/SDS-PAGE + functional myostatin binding assay)
- Suitable for muscle physiology, neuromuscular biology, and TGF-β signalling research laboratories
- Competitive research pricing with bulk options
