Matrixyl® 3000 is the trademarked combination of two palmitoylated matrikines developed by Sederma (Croda International), as documented by crodabeauty.com:
- Palmitoyl Tripeptide-1 (Pal-GHK)
- Palmitoyl Tetrapeptide-7 (Pal-GQPR)
Together, they synergistically modulate extracellular matrix (ECM) macromolecules, including collagen I, III, and IV, fibronectin, hyaluronic acid, and laminin-5, while influencing MMP-1 and inflammatory mediators (IL-6, IL-8) in laboratory models. This research-grade lyophilized blend is synthesized under strict quality controls and accompanied by full analytical documentation, making it suitable for cosmetic science, dermatology, and wound-healing research.
For Research Use Only. Not for human use.
Key Scientific Attributes
- High-purity Matrixyl® 3000 blend (≥98% total peptides by HPLC/MS)
- Exact 1:1 ratio of Pal-GHK + Pal-GQPR
- Lyophilized powder for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, MS, peptide content, and ratio verification
- Manufactured in GMP-aligned, ISO-compliant facilities
- Suitable for ECM remodeling, fibroblast activation, and dermal matrix research studies
Research-Referenced Attributes (Based on in-vitro and laboratory scientific literature; not intended as therapeutic claims. For research use only.)
- Observed increases in collagen I synthesis and fibronectin in human fibroblast in-vitro models, as noted by
- Observed modulation of dermal matrix components in photoaged skin research models
- Observed suppression of UV-induced MMP-1 and inflammatory cytokines (IL-6, IL-8) in laboratory studies
- Studied in combination with hyaluronic acid, vitamin C, and other cosmetic peptides in research contexts
Why Researchers Choose Nationwide Peptides Matrixyl® 3000
- Sederma-referenced sequences and exact 1:1 research ratio
- Transparent analytical data (HPLC >98%, MS confirmation of both peptides)
- Trusted by cosmetic-science, dermatology, and tissue-engineering laboratories
- Competitive research pricing with bulk powder and pre-mixed solution options
For Research Use Only. Not for human use.





