Kisspeptin Peptide
Kisspeptin Peptide
$55.00 $72.00Price range: $55.00 through $72.00 Select options

Kisspeptin Peptide

Price range: $55.00 through $72.00

For Research Use Only. Not for human use. Research-grade Kisspeptin-10 (Metastin 45-54), the minimal 10-amino-acid active core of kisspeptin-54 (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂), intended for controlled laboratory investigations of pulsatile GnRH release, LH/FSH signaling, and hypothalamic–pituitary–gonadal (HPG) axis regulation in research models.

For Research Use Only — Not for Human Consumption
 

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Kisspeptin-10 is the shortest biologically active fragment of the KISS1 gene product that fully retains potency at the kisspeptin receptor (KISS1R/GPR54). First identified in 2001 as the endogenous ligand associated with pubertal onset, it is now recognized as a key upstream regulator of pulsatile GnRH secretion in experimental models. According to published research, kisspeptin-10 activates GnRH neurons in the hypothalamus through G-protein-coupled receptor signaling, leading to downstream effects on LH and FSH secretion (ncbi.nlm.nih.gov). This research-grade lyophilized powder is synthesized under strict quality controls and provided with full analytical documentation. For Research Use Only. Not for human use.

Key Scientific Attributes

  • High-purity Kisspeptin-10 (≥99% by HPLC/MS, acetate or TFA salt form)
  • Verified native decapeptide sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
  • Lyophilized formulation for maximum long-term stability
  • Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
  • Manufactured in GMP-aligned, ISO-compliant facilities
  • Studied in the context of GnRH neuron activation and LH/FSH pulsatility research

Research Context (Based on scientific literature; not intended as therapeutic claims.)

  • Acts as an upstream regulator of GnRH secretion via KISS1R on hypothalamic GnRH neurons, as documented in neuroendocrine research (pmc.ncbi.nlm.nih.gov)
  • Used in experimental models investigating hypothalamic–pituitary–gonadal (HPG) axis signaling
  • The most commonly used kisspeptin fragment in biomedical research due to its defined receptor affinity and short sequence
  • Studied in reproductive neuroendocrinology, including investigations of GnRH pulse regulation and gonadotropin release

Why Researchers Choose Nationwide Peptides Kisspeptin-10

  • Active core sequence consistent with that used in published neuroendocrine research
  • Transparent analytical data (HPLC >99%, MS confirmation)
  • Trusted by reproductive endocrinology and neuroendocrinology laboratories
  • Competitive research pricing with bulk options

Additional information

Weight .125 lbs
Dimensions 9 × 7 × .5 in
Size: No selection

5mg, 10mg

Keep lyophilized peptides sealed in their original vial, protected from light and humidity, and store at -4°F or colder for optimal long-term stability in research settings; short-term refrigeration at around 39°F suffices for immediate use within weeks, though freezer storage maximizes integrity across extended research timelines.