Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by Russian scientist Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. It mimics the active core of epithalamin, a natural pineal peptide. In preclinical models, it has been studied for its interaction with telomerase and telomere maintenance pathways. Widely investigated in Russia for over 30 years in the context of gerontology and oncology research, it remains a subject of interest for pineal gland and geroprotective studies. According to a 2025 review published in the International Journal of Molecular Sciences, Epitalon demonstrates significant geroprotective and neuroendocrine effects in preclinical research (pmc.ncbi.nlm.nih.gov). This research-grade lyophilised powder is synthesised under strict quality controls and provided with full analytical documentation.
For Research Use Only. Not for human use.
Key Scientific Attributes
- High-purity Epithalon (≥99% by HPLC/MS, acetate salt form)
- Verified tetrapeptide sequence: Ala-Glu-Asp-Gly (AEDG)
- Lyophilized formulation for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
- Manufactured in GMP-aligned, ISO-compliant facilities
- Studied in the context of telomerase activation, telomere length, and pineal/melatonin research
Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims. For laboratory research use only.)
- Studied for telomerase enzyme interaction and telomere dynamics in human somatic cell cultures ()
- Investigated in preclinical longevity models, including fruit flies, mice, and human cell lines
- Studied the effects on pineal gland function and melatonin synthesis pathways in aging animal models
- Investigated in preclinical oncology research contexts, including immune-related endpoints
- Subject of oxidative stress and metabolic parameter research in preclinical settings
- Used in gerontology, oncology, and circadian rhythm research applications
Why Researchers Choose Nationwide Peptides Epithalon
- Exact Russian research-study sequence (AEDG) as used in Khavinson laboratory studies
- Transparent analytical data (HPLC >99%, MS confirmation)
- Trusted by gerontology, oncology, and longevity research laboratories
- Competitive research pricing with bulk options






