MOTS-c is a mitochondrial-encoded peptide discovered in 2015, encoded within the 12S rRNA region of mtDNA. Under metabolic stress conditions, it translocates to the nucleus to regulate genes involved in energy homeostasis and glucose metabolism. This research-grade lyophilized peptide is synthesized under strict quality controls and provided with full analytical documentation, making it suitable for mitochondrial signaling and metabolic research applications. For Research Use Only. Not for human use.
Key Scientific Attributes
- High-purity MOTS-c (≥99% by HPLC/MS, acetate salt form)
- Verified 16-amino-acid sequence: Met-Arg-Trp-Leu-Ser-Leu-Leu-Arg-Ser-Pro-Pro-Gly-Leu-Ala-Trp-Leu-Arg-Leu-Phe-Gly
- Lyophilized formulation for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
- Manufactured in GMP-aligned, ISO-compliant facilities
- Suitable for AMPK activation studies, mitochondrial retrograde signaling research, and metabolic pathway investigations
Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)
- Studied for its role in AMPK phosphorylation and GLUT4 translocation in preclinical models
- Investigated in relation to glucose uptake mechanisms in skeletal muscle cell studies
- Subject of research into inflammatory cytokine modulation (IL-6, TNF-α) in laboratory settings
- Used in preclinical mitochondrial biology and metabolic pathway research
Why Researchers Choose Nationwide Peptides MOTS-c
- The exact human mitochondrial-encoded sequence referenced in published scientific studies
- Transparent analytical data (HPLC >99%, MS confirmation)
- Trusted by mitochondrial biology and metabolism laboratories
- Competitive research pricing with bulk options
For Research Use Only. Not for human use. Not intended to diagnose, treat, cure, or prevent any condition.
